摘要
心肌梗死的传统诊断方式(心电图、心肌酶学等)方便实用,但仍然存在着假阴性及疑似阳性的情况,并且难以对预后做出评估。核素分子影像学技术根据疾病病理生理机制寻找可构建放射性标记特异位点,以此制作分子探针,动态反映疾病的发展过程或组织脏器的功能情况;体外利用核素分子探测仪单光子发射计算机断层显像和正电子发射计算机断层显像探测梗死心肌信息,指导临床治疗和评估预后信息。该文就核素分子影像学在心肌梗死方面的现状和研究进展进行综述。
Traditional diagnostic methods for myocardial infarction ( such as electrocardiogram,cardiac enzymes,etc) are convenient and practical,although there are still occurrence of false negative and suspected positive cases,which makes it hard to assess the prognosis.Nuclide molecular imaging technology can build specific sites of radioactive labeling basing on pathophysiological mechanisms of the disease to make molecu-lar probes,and dynamically reflect the progression of the disease or the function of the organization .Single photon emission computed tomography and positron emission tomography using Radionuclide molecule detec-tor in vitro can detect status of myocardial infarction, in order to provide guidance for clinical treatment and assessment of the prognosis.Here is to make a review of the status and research progress on nuclide molecular imaging in myocardial infarction .
出处
《医学综述》
2015年第11期2039-2041,共3页
Medical Recapitulate
基金
四川省卫生厅科研课题(130336)
关键词
心肌梗死
核素分子影像学
诊断
Myocardial infarction
Nuclide molecular imaging
Diagnosis