催化合成典型5-羟甲基糠醛衍生物的研究进展

Progress of catalytic synthesis of typical 5-hydroxymethyl furfural derivatives

作为重要的生物基平台化合物之一,5-羟甲基糠醛(HMF)可通过可再生的生物质碳水化合物脱水制备,已获得广泛关注,HMF可以催化合成一系列重要的有机化工中间体,这逐渐成为研究热点。本文综述了5-羟甲基糠醛制备2,5-二甲酰基呋喃(DFF)、2,5-呋喃二甲酸(FDCA)和1,6-己二醇(HDO)三种典型HMF衍生物的研究进展,并着重分析了HMF选择氧化制备DFF和FDCA的催化体系。介绍了该三种重要有机化工中间体的相关应用,分析其制备过程中的问题与难点,对其今后的研究方向提供了建议,并指出目前HMF未大规模工业生产导致其价格昂贵,是制约下游产品发展的重要因素。采用生物质为原料,通过5-羟甲基糠醛催化合成下游有机化工产品的研究具有广阔的前景。

As one of important bio-based platform chemicals,5-hydroxymethyl furfural （HMF） could be produced by dehydration of renewable biomass carbohydrates. HMF could catalyze synthesis of a series of important organic chemical intermediates,and has become a research hot topic. Research progress of preparations from 5-hydroxymethyl furfural （HMF） to 2,5-diformylfuran （DFF） , 2,5-furandicarboxylic acid （FDCA） and 1,6-hexanediol （HDO）,as three important HMF derivatives is reviewed,especially the catalytic system for HMF selective oxidation of preparing DFF and FDCA. Related application of the three important organic chemical intermediates is introduced,and problems and difficulties in the preparation process are analyzed to provide advices for further research. HMF is not large-scale produced so it is very expensive,which restricts the development of downstream products. The research using 5-hydroxymethyl furfural to catalyze synthesis of organic chemical products from biomass materials will have broad prospect.