期刊文献+

基于GRIN透镜的内窥OCT探头设计 被引量:1

Design of endoscopic OCT probe based on GRIN lens
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摘要 提出一种用于在体活检的光谱OCT内窥探头的设计方案,能够实现对生物组织器官深度信息的在体内快速动态实时扫描成像,在临床医学领域具有广阔的应用前景。文中对探头的设计进行了理论分析,对探头的加工和测试进行了系统的阐述。针对传统的GRIN探头设计,本文探头的设计提高了光学质量和机械健壮性。对于OCT探头的成像质量依赖于单模光纤和GRIN透镜之间的距离(玻璃垫片长度),进行了建模和验证。实验得出将玻璃垫片长度控制在0.2 mm左右,探头可以达到2 cm左右的工作距离,工作距离范围内探头的远场光束发散角为0.0175°。 A design of OCT endoscopic probe for tissue biopsy is proposed,and this probe can be used for real time imaging of tissue profile based on tissue depth information,so it has broad prospect in clinical application.The design of probe was theoretically analyzed,and then the process and measurement of the probe were elaborated in de-tail.Compared with the traditional probe,the proposed probe can improve the optical quality and machine robust.The principle that the image quality depends on the distance between single mode fiber and GRIN lens was modeled and verified.The experimental results show that,when the length of glass spacer is about 0.2 mm,the working distance of the probe reaches about 2 cm and its divergence angle of far field is 0.01 75°.
出处 《激光与红外》 CAS CSCD 北大核心 2015年第6期678-682,共5页 Laser & Infrared
基金 机械制造系统工程国家重点实验室开放基金(No.sklms201309) 江苏省科技支撑项目(No.BE2013605)资助
关键词 OCT 探头 ABCD 矩阵 MATLAB 仿真 内窥成像 机械健壮性 OCT probe ABCD matrix Matlab simulation endoscopic imaging machine robust
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参考文献11

  • 1SoroorBehbahani, Keivan maghooli ,et al. Analysis of opti- cal coherent tomography[ C]. CISP,2008:448 -451.
  • 2G J Tearney, M E Brezinski, B E Bouma, et al. In vivo en- doscopic optical biopsy with optical coherence tomography [ J ]. Science, 1997,276 (27) :2037 - 2039.
  • 3Xingde Li, Christian Chudoba, Tony Ko, et al. Imaging needle for optical coherence tomography [ J ]. Optical Let- ters,2000,25 (20) : 1520 - 1522.
  • 4李乔,高长磊,陈晓冬,郁道银.基于旋转扫描探头的OCT内窥成像系统设计[J].光子学报,2009,38(10):2650-2653. 被引量:5
  • 5梁燕,刘铁根,王佳佳,孟卓,兰寿锋,姚晓天.基于全光纤相干层析系统快速扫描探头的研制[J].激光与红外,2008,38(12):1233-1236. 被引量:3
  • 6Yoshiyuki Takahashi, Mitsuharu Iwaya, Yuuki Watanabe, et al. Optical probe using eccentric optics for optical co- herence tomography [ J ]. Optics Communications, 2007, 285 - 290.
  • 7Wladimir A. Benalcazar, Woonggyu Jung, Stephen A. Bop- part,et al. Aberration characterization for the optimal de- sign of high-resolution endoscopic optical coherence tomo- graphy catheter [ J ]. Optics Letters, 2012, 37 ( 6 ) : 1100 - 1102.
  • 8X D Li, C Chudoba, T Ko, C Pitris, et al. Imaging needle for optical coherence tomography [ J ]. Optics Letters, 2000,25 : 1520 - 1522.
  • 9Minseog Choi, Seungwan Lee,Jong-hyeon Chang, et al. A- daptive optical probe design for optical coherence tomo- graphy and microscopy using tunable optics [ J ]. Optics Express ,2013,21 (2) : 1567 - 1573.
  • 10邱锦辉,梅荣华.ABCD矩阵与高斯光束光学系统的讨论[J].光学仪器,1991,13(3):25-32. 被引量:5

二级参考文献18

  • 1朱晓农,毛幼馨,梁艳梅,贾亚青,母国光.光学相干层析系统噪音分析(Ⅰ)——理论与计算[J].光子学报,2007,36(3):452-456. 被引量:18
  • 2朱晓农,毛幼馨,梁艳梅,贾亚青,母国光.光学相干层析系统噪音分析(Ⅱ)——时域OCT和频域OCT[J].光子学报,2007,36(3):457-461. 被引量:12
  • 3A F Fercher,W Drexier, C K Hitzenberger, et al. Optical coherence tomography-principles and applications [ J ]. Reports on progress in Physics ,2003,66 (2) :239- 303.
  • 4Swanson E A, Izatt J A, et al. In-vivo retinal imaging by optical coherence tomography [ J ]. Opt. Lett. , 1993,18, 1864.
  • 5S A Boppart, B E Bouma, C Pitris, et al. Forward-imaging instruments for optical coherence tomography [ J ]. Optics Letters, 1997,22 (21) : 1618 - 1620.
  • 6X D Li,X M Liu, Y C Chen, et al. Development of fast scanning miniature probe and method of dispersion management for high-resolution optical coherence tomography [ J]. Proceeding of the 26^th Annual International Conference of the IEEE EMBS San Francisco, CA, USA: September,2004,1 (5) :5289 - 5291.
  • 7Yingtian Pan,Huikai Xie,Gary K Fedder. Endoscopic optical coherence tomography based on a microelectromechanical mirror[ J ]. Optics Letters ,2001,26, (24) : 1966 - 1968.
  • 8J M Zara,S Yazdanfar, K D Rao, et al. Electrostatic micromachine scanning mirror for optical coherence tomography [ J ]. Optics Letters,2003,28 ( 8 ) :628 - 630.
  • 9Woonggyu Jung, Daniel T McCormick, Jun Zhang, et al. Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror [ J ]. Applied Physics Letters, 2006, 88 : 163901.
  • 10Peter H Tran, David S Mukai, Matthew Brenner, et al. In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe [ J]. Opics Letters,2004 ,29( 11 ) : 1236 - 1238.

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