期刊文献+

紫杉醇联合顺铂新辅助化疗对局部晚期宫颈癌的近期疗效观察 被引量:2

下载PDF
导出
摘要 目的分析紫杉醇联合顺铂新辅助化疗对局部晚期宫颈癌的近期疗效。方法选取局部晚期宫颈癌患者74例随机分为2组,2组患者均行广泛子宫切除术与盆腔淋巴结清扫术。对照组36例术前不进行化疗,观察组38例术前给予紫杉醇联合顺铂新辅助化疗,对比2组的近期疗效。结果对照组完全缓解10例,部分缓解5例,稳定17例,进展4例,治疗总有效率为41.7%;观察组完全缓解22例,部分缓解9例,稳定6例,进展1例,治疗总有效率为81.6%,观察组治疗总有效率显著高于对照组(P<0.05)。结论在局部晚期宫颈癌的治疗中,采用紫杉醇联合顺铂行新辅助化疗效果显著,不良反应均可在患者可耐受范围内,值得在临床上推广。
作者 雒润华
出处 《基层医学论坛》 2015年第18期2487-2488,共2页 The Medical Forum
  • 相关文献

参考文献3

二级参考文献45

共引文献53

同被引文献49

  • 1蒋丰,陈忠东.晚期宫颈癌的治疗新进展[J].医学信息(医学与计算机应用),2014,0(7):516-516. 被引量:3
  • 2Siegel RL, Fedewa SA, Miller KD, et al. Cancer statistics for His- panics/Latinos, 2015 [ J]. CA Cancer J Clin, 2015,65 (6) : 457- 480.
  • 3McCormack PL. Quadrivalent human papillomavirus, recombinant vaccine : a review of its use in the prevention of premalignant ano- genital lesions, cervical and anal cancers, and genital warts [ J]. Drugs,2014,74(ll) :1253-1283.
  • 4Joura EA,Kjaer SK, Wheeler CM, et al. HPV antibody levels and clinical efficacy following administration of a prophylactic quadriva- lent HPV vaccine [J]. Vaccine, 2008,26 (52) : 6844-6851.
  • 5Malagon T, Drolet M, Boily MC, et al. Cross-protective efficacy of two human papillomavirus vaccines: a systematic review and meta- analysis [ J] .The Lancet. Infectious diseases, 2012, 12 (10) :781- 789.
  • 6Markowitz LE, Dunne EF, Saraiya M, et al. Human papillomavirus vaccination : recommendations of the Advisory Committee on Immu- nization Practices ( ACIP).MMWR.Recommendations and reports : Morbidity and mortality weekly report [ J]. Recommendations and reports / Centers for Disease Control, 2014,63 ( Rr-05 ) : 1-30.
  • 7Reagan-Steiner S, Yankey D, Jeyarajah J,et al.National, Region- al, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13-17 Years-United States, 2014 [J]. MMWR Morb Mortal Wkly Rep, 2015,64 (29) : 784-792.
  • 8Dargent D, Brun JL, Roy M, et al. Pregnancies following radical trachelectomy for invasive cervical cancer [ J]. Gynecol Oncol. 1994,52:105.
  • 9Smith JR, Boyle DC, Corless DJ, et'al.Abdominal radical trachelec- tomy: a new surgical technique for the conservative management of cervical carcinoma [ J~. Br J Obstet Gynaecol, 1997, 104 (10) : 1196-200.
  • 10Lee CL, Huang KG,Wang C J, et al. Laparoscopic radical trachelec- tomy for stage Ibl cervical cancer [ J3 .J Am Assoc Gynecol Lapa- rosc, 2003,10 ( 1 ) : 111-115.

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部