慢性乙肝患者心理弹性与生存质量相关性研究

Study on the relationship between resilience and the quality of life in patients with chronic hepatitis B

目的探讨慢性乙型肝炎患者的心理弹性和生存质量状况及二者的相关性,便于未来以心理弹性为基础,为患者的生活质量相关干预研究提供依据。方法采用便利抽样方法,选取郑州大学第二附属医院符合纳入和排除标准的80例慢性乙肝患者,运用心理弹性量表(CD-RISC)和慢性肝病特异性量表(CLDQ)调查其目前的心理弹性水平和生存质量状况。结果慢性乙肝患者心理弹性总分为(52.60±19.77)分,CLDQ得分为(3.34±0.54)分,皆处于较低水平;一般资料方面与心理弹性总分进行方差分析,结果表明不同年龄组患者心理弹性总分排序为:大于60岁组>45~59岁组>18~44岁组,差别有统计学意义(P<0.05);Pearson’s相关性分析结果显示:心理弹性总分与生存质量总分及部分维度(腹部症状、乏力、全身症状、情绪功能、焦虑)呈显著负相关(r=-0.737^-0.991,P<0.05),而与活动维度相关性差异无统计学意义(r=-0.737,P>0.05)。结论慢性乙型肝炎患者心理弹性水平和生存质量普遍较低,心理弹性水平高低会影响患者的生存质量,因此临床上应指导慢性乙肝患者,尤其是年轻患者采取有效措施提升心理弹性水平,以提高其生存质量。

Objective Survey the current situation of resilience and quality of life in the patients with chronic hepatitis B,in order to explore their relationship and provide the basis for the intervention study about quality of life of patients. Methods Using convenience sampling method,80 patients with chronic hepatitis B from our hospital were surveyed with the Connor-Davidson Resilience Scale（ CD-RISC） and Chronic Liver Disease-specific Questionnaire（ CLDQ） who met the inclusion criteria,and then conducted the analysis. Results The score of CD-RISC was 52. 60 ± 19. 77. The score of the CLDQ was 22. 23 ± 0. 92. They were in a low level. The analysis of variance between the general information and the score of CD-RISC showed that the score of CD-RISC in three age groups was different（ more than 60 years old group 45 to 59 18 to 44 age group）. The difference was statistically significant（ P 〈0. 05）. Pearson＇s correlation analysis results showed that the CD-RISC of patients with chronic hepatitis B was negatively correlated with the score of the quality of life,abdominal symptoms,fatigue,systemic symptoms,anxiety and emotional function（ r =- 0. 737 to- 0. 991,P 〈0. 05）.There was no statistically significant difference between the score of activity dimension and the CD-RISC（ r = 0. 737,P 〉0. 05）. Conclusion The level of resilience and survival quality was generally low for chronic hepatitis B patients. The level of resilience was an important factor affecting the quality of life of patients. Therefore,the patients with chronic hepatitis B,especially young patients,should be instructed to take effective measures to enhance the level of resilience,in order to improve the quality of life.