经支气管镜诊断的肺癌1761例临床对比分析

Comparative Analysis of 1761 Patients with Lung Carcinoma Diagnosed by Bronchoscopy

目的分析近20 a经支气管镜诊断的肺癌病例前10 a和后10 a中男女比例、病理类型及男女发病年龄的变化,探讨肺癌的发病特点。方法对1993年1月至2012年12月20 a间经支气管镜诊断的1 761例肺癌患者的临床资料进行回顾性分析。结果前、后10 a男女比例分别为3.22∶1和3.15∶1,其中青年肺癌前、后10 a男女比例分别为1.30∶1和4.80∶1。前、后10 a鳞癌、腺癌、小细胞癌分别占50.84%、13.53%、31.94%和49.34%、16.93%、30.03%,其中女性腺癌前、后10 a分别占同期肺癌的6.67%和7.28%,男性腺癌前、后10 a分别占同期肺癌的6.86%和9.66%。前10 a肺癌年龄(57.12±12.03)岁,其中男性年龄(57.73±12.25)岁,女性年龄(55.44±11.98)岁;后10 a肺癌年龄(60.03±11.86)岁,其中男性年龄(60.14±12.11)岁,女性年龄(59.75±11.37)岁。结论本组肺癌前、后10 a男女比例变化不大,但青年肺癌男女比例明显增高,男性患者明显增多;男女腺癌占全部肺癌的比例均呈上升趋势;肺癌发病年龄有后延趋势。

Objective To analysis the male/female ratio, pathological type, change between male/female onset age of patients with lung carcinoma diagnosed by bronchoscopy between the first decade and second decade of nearly 20 years, and to investigate the disease characteristics of lung carcinoma. Methods The data of 1 761 patients with lung carcinoma diagnosed by bronchoscopy were analyzed retrospectively from January 1993 to December 2012 Results Among the lung carcinoma of the first decade and second decade, the male/female ratio was 3.22 ： 1 and 3.15 ： 1 ,the male/female ratio of young lung carcinoma was 1.30：1 and 4.80：1 respectively; the ratio of squa- mous cell carcinoma, adenocarcinoma and small cell carcinoma were 50.84% , 13.53% , 31.94% and 49.34%, 16.93 % , 30.03 % respectively, the female adenoearcinoma accounted for 6.67 % and 7.28% respectively, the male adenocarcinoma accounted for 6.86% and 9.66% of all the lung carcinoma respectively. Among all the lung carcinoma cases of the first decade, the age was （ 57.12 ± 12.03 ） years old, the male and female was （57.73 ± 12.25 ） and （55.44 ± 11.98 ） years old respectively; among all the lung carcinoma of the second decade, the age was （60.03 ±11.86） years old,the male and female was （60.14 ± 12.11 ） and （59.75 ± 11.37） years old respectively. Conclusion Among this group of lung carcinoma, there was a little change of the male/female ratio, but the young patients ratio was increased significantly, with the male patients ratio was increased obviously at the same time ; the male and female adenocarcinoma ratio all showed a trend of rising among all the patients ; the onset age of lung carcinoma has the delayed trends.