穴位注射配合西药治疗腹泻型肠易激综合征的疗效观察

Observations on Acupuncture Point Injection Astragalus Injection Combined with Western Medicine on Diarrhea-predominant Irritable Bowel Syndrome

目的观察黄芪注射液穴位注射配合西药曲美布汀治疗腹泻型肠易激综合征的临床疗效。方法将96例腹泻型肠易激综合征患者随机分为治疗组和对照组,其中治疗组47例,对照组49例。2组患者均口服曲美布汀,每次1片,3次/d,共服用2周,治疗组在此基础上采用黄芪注射液穴位注射,选穴:心俞、肝俞、脾俞,隔日1次,共治疗7次。2组患者采用IBS-SSS量表对患者治疗结束时、治疗结束后1个月和3个月临床症状改善情况进行评价。结果治疗结束时2组患者IBS-SSS评分均较治疗前有显著改善,差异具有统计学意义(P<0.05),在治疗结束时和治疗后1个月,2组组间比较差异有统计学意义(P<0.05),治疗组优于对照组,但治疗后3个月,2组差异无统计学意义(P>0.05)。在临床症状改善方面,治疗组在腹痛程度和腹痛频率方面改善明显优于对照组,差异有统计学意义(P<0.05)。结论黄芪注射液穴位注射配合曲美布汀治疗腹泻型肠易激综合征有良好的临床疗效,可以明显改善患者腹痛或腹胀等主要症状。

Objective To investigate the effect of acupuncture point injection astragalus injection combined with trimebutine on diarrhea-predominant irritable bowel syndrome（IBS-D）. Methods Using the randomized controlled method,ninety-six IBS-D were divided into a treatment group（47 cases）and control group（49 cases）. Both groups received trimebutine,one tablet each time, three times a day,taking two weeks,the treatment group received point Xinshu,Ganshu,Pishu injection of astragalus in addition,a total of seven times in treatment. After two weeks,using the IBS-SSS scale for patients at the end of the treatment,one month and three months to evaluate clinical synmptoms improve the situation. Results IBS-SSS score was improved significantly after treatment in the two groups（P〈0.05）,and the improvements in the treatment group were superior to those in control group after treatment and 1 month（P〈0.05）,however,3 month after treatment in the two groups there was no statiscally significant difference（P〉0.05）. In terms of clinical symptoms improved,the treatment group improved in terms of frequency of abdominal pain and abdominal pain was better than control group,the difference was statistically significant（P〈0.05）. Conclusion The method of acupuncture point injection astragalus injection combined with trimebutine can alleviate the symptoms of IBS-D and it is effective.