北京社区老年人群缺牙数与认知障碍的关系

The interrelationship between tooth loss and cognitive impairment-A community based study in Beijing

目的:探讨北京社区老年人群牙齿缺失数量与认知障碍的关系。方法:研究对象为北京市石景山区4个社区的受试者1058人,对有完整人口学数据、全身检查、血生化指标、牙周检查指标以及简明智能检查表(Mini-Mental State Examination)且年龄≥60岁的共666人进行统计分析。结果:缺牙数与认知障碍,在排除了包括性别、年龄、社会经济因素、全身健康因素以及烟酒嗜好等传统危险因素后有显著相关,β=-0.035(95%CI:-0.056,0.014,P=0.001)。结论:缺牙数与认知障碍有显著相关性,但两者的因果关系需要进一步的探讨。

Objective： To study the relationship between tooth loss and cognitive impairment based on a community in Beijing. Methods： 1058 subjects from 4 communities at Shijingshan, Beijing participated in this study. At last, 666 people of 60 yr or older with complete data of demographic data, socioeconomic status, systemic health status, blood biochemical indexes, periodontal parameters and Mini-Mental State Examnation（MMSE） scores were enrolled in our study. Results： Tooth loss was correlated with cognitive impairment when adjusted for all the confounding factors （including age,sex, socia-economic status, systemic health status, drinking and smoking habits） β=-0.035 （95% CI： -0.056, 0.014;P=-0.001）. Conclusion： Tooth loss is significantly correlated with cognitive impairment, but the causal relationship needs to be explored further from perspective studies.