婴幼儿轻度胃肠炎继发良性惊厥20例临床与视频脑电图分析

Clinical study and VEEG analysison of 20 cases mild gastroenteritis with benign infantile convulsions

目的 分析婴幼儿轻度胃肠炎继发良性惊厥的临床与视频脑电图情况.方法 婴幼儿轻度胃肠炎继发良性惊厥20例,用免疫金标记技术进行病原学诊断,并进行实验室、影像学和视频脑电图检查.结果 惊厥发生时间以急性胃肠炎后3天以内最多,占总病例之80％.惊厥发生次数以发作1～2次者最多,占总病例之95％.惊厥发作形式主要为全身强直阵挛性,发作后无烦躁不安、嗜睡、精神萎靡等.颅部CT和MRI检查结果多为正常.发作期视频脑电图检查见异常放电多起源于中央顶部和枕部,发作波节律多呈低波幅快波,发作间期均无癫痫样放电.病原学检测结果显示轮状病毒感染为主,实验室检查结果多在正常范围.结论 婴幼儿轻度胃肠炎继发良性惊厥是具有独特特征的一种临床病症.

Objective To analyze clinical aspects and video electroencephalogram （VEEG） of infants with mild gas- troenteritis with benign infantile convulsions. Methods 20 eases of infant patients with mild gastroenteritis with be- nign infantile convulsions were undergone with immune etiology diagnosis gold labeling technique, and for laborato- ry, imaging and VEEG examination. Results Seizures occurred mostlyin 3 days after acute gastroenteritis, accoun- ted for 80% of the cases. The number of seizures in the course ofthe disease is1 or 2 times,accounted for 95%. The convulsions manifestations generalized tonic -clonic seizures, no dysphoria, drowsiness and mental fatigue after the attack. Cranial CT and MRI results are normal. Episodes video electroencephalogram examination have shown ab- normal discharge originated in more the top and occipital, and the rhythmof attack wave showed low amplitude fast wave, without epileptiform discharges. Etiology detection results showedmainlyrotavirus infection. Laboratory test re- sults werein the normal range. Conclusion Benign infantile convulsionwith mild gastroenteritis is a unique feature of a clinical disorder in infants and young children.