高危型人乳头瘤病毒感染与育龄女性宫颈糜烂程度及类型关系的研究

Analysis of the relationship between HR-HPV infection and cervical erosion in women of childbearing age

目的:探讨分析育龄妇女宫颈糜烂与高危型人乳头瘤病毒(HR-HPV)感染的关系。方法:选取治疗的150例患宫颈糜烂的育龄妇女作为研究对象,采用第二代杂交捕获技术对HR-HPV进行筛查,将HR-HPV的感染情况同宫颈糜烂的程度及类型进行统计学分析。结果:宫颈糜烂Ⅰ度、Ⅱ度、Ⅲ度的HR-HPV感染率分别为11.4%、35.6%和38.3%,单纯型、乳头型、颗粒型宫颈糜烂的HR-HPV感染率分别为16.3%、53.8%和24.2%,Ⅱ度和Ⅲ度宫颈糜烂的感染率较Ⅰ度宫颈糜烂具有显著性差异(P<0.05),单纯型和颗粒型宫颈糜烂的感染率较乳头型具有显著性差异(P<0.05)。结论:宫颈糜烂育龄妇女患者易感染HR-HPV,二者呈正相关。

Objective：To study the correlation between cervical erosion in women of childbearing age and high risk human papillomavirus （ HR-HPV） infection.Methods：150 cases of cervical erosion in women of childbearing age were selected.HR-HPV was detected by using the Hybrid Capture and the correlation between HR-HPV infection and the degree and the type of cervical erosion were statistically analyzed .Results：The HR-HPV infection rates of cervical erosion degreeⅠ,Ⅱ,Ⅲwere 11.4 %, 35.6 %and 38.3 %respectively.Compared with the infection rate of cervical erosion degreeⅠ, the difference between that of degree Ⅱ and Ⅲ was significant （ P 〈0.05）.The HR-HPV infection rates of simplex, papillary and granular cervical erosion were 16.3 %, 53.8 %and 24.2 %respectively.Compared with the infection rate of the papillary cervical erosion, the difference between that of the granular and simplex cervical erosion of degree was significant （ P 〈0.05）.Conclusion：Pa-tients with cervical erosion is easily infected by HR -HPV and there is a positive correlation between them.