针刺联合西药治疗贝尔面瘫有效性系统综述与Meta分析

Systematic Review and Meta-analysis in Effect of Acupuncture Comebined Westem Medicine on Treating Bell's Palsy

[背景]单纯针刺与单纯西药治疗贝尔面瘫均疗效确切。[目的]评价针刺联合西药治疗差异性。[检索策略]主题词与自由词相结合检索CNKI、VIP、Wan Fang Data、Pub Med、Cochrane library等数据库,检索时间:建库至2014年10月。同时追溯纳入文献参考文献。[纳入标准]中、英文随机对照试验(RCT)文献。1研究对象:符合诊断标准,不限年龄和性别。2干预措施:试验组单纯针刺或针刺+西药,对照组单纯西药。3结局指标:临床疗效。[数据收集与分析]2位研究者根据纳入标准,比较同质性文献,独立筛选文献评价,不一致时讨论解决。采用资料提取表,提取内容:样本量、性别、年龄、疗程、干预措施、结局指标等。[主要结果]最终纳入文献JADAD评分:3篇2分,作定量分析;1篇3分,作定性分析。单纯针刺与单纯西药治疗比较:痊愈(P=0.01<0.05);显效(P=0.77>0.05),有效(P=0.25>0.05)。针刺联合西药与单纯西药治疗比较:痊愈(P=0.05),有效(P=0.02<0.05),显效(P=0.009<0.05)。[结论]单纯针刺痊愈优于单纯西药治疗;有效、显效无显著差异。针刺联合西药治疗有效和显效均优于单纯西药治疗;针刺联合西药与单纯西药治疗痊愈无显著差异。[问题与展望]纳入文献质量低,文献量少;证据还需要高质量大样本随机对照试验支持。

[Background] It is positive to effect of acupuncture or westem medicine on treating Bell＇s palsy.[Purpose]To evaluate effect of acupuncture comebined westem medicine on treating Bell＇s palsy.[Researing Method] Datebase had been retrieved from creating of database to October 2014 year in CNKI Data,VIP Data,Wan Fang Data,Pub Med Data,and Cochrane library.At the same time,researching references of randomized controlled trials in subject word and random word. [Selection Criteria]（i）languages belong to Chinese or English of randomized controlled trials（RCT）.[Object of Study]the study besides Different age and sex was accepted if it was accorded with diagnostic criteria of Bell＇s Palsy.（ii）Intervening Measures：the treatment group was given with acupuncture or westem medicines,the control group was given only to westem.（iii）Outcomes：Clinical Performance Indicators of trials.Data Collection and Analyses：Literatures of homogeneity were strictly filtrated and evaluated through two authors independently according to Selection criteria.literatures of divergence were comed to an agreement by discussion.data were extracted with tables that include sample size,sex,age,course of treatment,intervening measures,and criterion of therapeutical effect and so on.[Main Results] Three literatures of two scores and one literature of three scores were evaluated with JADAD table.the former was analysed quantitatively and the later was analysed qualitatively.Bell＇s Palsy was healed completely well（P=0.010.05）,and had marked effect（P=0.770.05）,and had effect（P=0.250.05） by treating of acupuncture compared with simplex westem medicine.however,comparing acupuncture combined westem medicine with simplex westem medicine. Bell＇s Palsy was healed completely well（P=0.05）,and had marked effect（P=0.0090.05）,and had effect（P=0-020.05）.[Conclusions]The recovered effect of acupuncture compared with simplex westem medicine was better, and obvious effect or effective effect was equal. Moreover,it was better to the obvious effect and effective effect of acupuncture combined westem medicine compared with simplex westem medicine,and the recovered effect was equal.[Questions and Outlooks]The inclusion literatures is low quality,and less quantity.the results need more randomized controlled trials of high-quality and large-scale samples to sustain it.