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宫腔手术对子宫内膜容受性的影响 被引量:1

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摘要 目的:探讨宫腔手术史(包括人流术、诊刮术)患者对子宫内膜容受性的影响。方法回顾性分析2014年1月至2015年1月在新疆自治区第二济困医院妇产科门诊不孕症就诊患者115人,分为观察组和对照组,55例曾有宫腔手术史为观察组,60例无宫腔手术史为对照组。通过阴道超声测量排卵前一天,排卵后5~7 d子宫内膜平均厚度与类型,比较两组患者子宫内膜厚度、类型及临床妊娠率、胚胎着床率和自然流产率的差异。结果观察组和对照组患者平均年龄、不孕年限、BMI值、基础FSH值、雌二醇(E2)值,孕酮(P)值差异均无显著性(P>0.05)。观察组和对照组两组患者分别于排卵前一天,排卵后5~7 d天子宫内膜平均厚度差异均有显著性(P〈0.05);两组的子宫内膜类型虽然差异无统计学意义(P>0.05),但观察组在排卵前一天,排卵后5~7 d中A型子宫内膜比例较对照组均低,而B型和C型内膜比例绝大部分高于对照组的相应类型;随着宫腔手术次数增加,观察组临床妊娠率、活产率分别为33.7%、24%,均低于对照组的41.3%、31%,而自然流产率为21%高于对照组的15%。差异均无显著性(P>0.05)。结论宫腔手术史可通过改变子宫内膜厚度、类型来影响子宫内膜容受性,从而影响妊娠结局。
出处 《新疆医学》 2015年第5期604-607,共4页 Xinjiang Medical Journal
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