结直肠息肉患病的相关因素分析

Study on related factors of colorectal polyps

[目的]探讨结直肠息肉患病的相关因素。[方法]通过结肠镜检查将接受结直肠息肉筛检的对象分为病例组和对照组,并通过问卷调查相关高危因素。采用Logistic回归分析探讨肠息肉的相关因素。[结果]共纳入结直肠息肉患者154例,正常对照组98例。多因素Logistic回归分析显示,男性（OR为2.65,95%CI为1.17~6.00）、肥胖（OR为4.80,95%CI为1.16~9.94）、肠息肉家族史（OR为10.19,95%CI为1.19~17.26）、脂肪摄入过多（OR为3.24,95%CI为1.46~7.20）的对象患肠息肉的相关风险更高。[结论]肠息肉患病与男性、肠息肉家族史、脂肪摄入过多和肥胖等因素存在相关关系。相关因素问卷调查有助于针对性地开展结直肠肿瘤筛查。

[ Objective ] To explore the related factors of colorectal polyps. [ Methods ] Participants were divided into polyps group and control group according to colonoscopy. The possible risk factors were investigated by questionnaire. Logistic regression analysis was conducted in order to explore the related factors of colorectal polyps. [ Results] A total of 252 participants （154 in polyps group, 98 in control group ） were enrolled in the current study. Multivariate Logistic regression analysis showed that those with higher odds ratio of colorectal polyps were among male （OR： 2. 65, 95% CI： 1. 17 -6. 00） and obesity（OR： 4. 80,95% CI： 1. 16 -9. 94）, among those with family history of colorectal polyps（OR： 10. 19, 95 % CI： 1.19 - 17.26 ）, and those with high proportion of fat intake （ OR ： 3.24, 95 % CI： 1.46 - 7.20）. [ Conclusion ] Male, obesity, family history of colorectal polyps and high proportion of fat intake are the related factors of colorectal polyps. And investigation by related factors questionnaire facilitates the targeted screening of colorectal tumors.