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2型糖尿病与HER2过表达型乳腺癌预后的相关性研究

Relationship of Type 2 Diabetes with Prognosis of the HER-2 overexpressed Breast Cancer Patients
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摘要 目的分析2型糖尿病与HER2过表达型乳腺癌预后的相关性。方法比较不合并2型糖尿的HER2过表达型乳腺癌患者与合并2型糖尿病的HER2过表达型乳腺癌患者在巩固期治疗后短期内的转移、复发与死亡率的差异。结果在HER2过表达型乳腺癌患者中,合并2型糖尿病的患者复发转移率与死亡率均高于不合并2型糖尿病的患者,差异有显著性(P<0.05)。结论 2型糖尿病对HER2过表达型乳腺癌的预后不良有促进作用。 Objective To explore the relationship of the type 2 overexpressed breast cancer. Methods Through a follow -up in diabetes and prognosis of the HER -2 HER- 2 overexpresssion breast cancer patients during the period of consolidating the therapeutic effect, the recrudescence and metastasis rate and the fatality rate of patients with type 2 diabetes were compared with those of patients with normal blood sugar. Results The recrudescence and metastasis rate and the fatality rate in HER -2 overexpressed breast cancer patients with type 2 diabetes were significantly higher than the patients with normal blood sugar (P 〈 0. 05). Conclusion The prognosis of the HER - 2 overexpressed breast cancer may correlate with the type 2 diabetes.
出处 《广东微量元素科学》 CAS 2015年第4期39-41,共3页 Trace Elements Science
关键词 2型糖尿病 HER2过表达型乳腺癌 预后 Type 2 diabetes HER -2 overexpressed breast cancer prognosis
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参考文献4

  • 1HARARID D, YARDEN Y. Molecular mechailismg underlying ErbB2/HER2 action in breast cancer [ J ]. Oneogene, 2000, 19 (53): 6102-6114.
  • 2YANG X, KO G T, SO W Y, et al. Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hang Kong diabetes registry [J]. Diabetes, 2010, 59 (5) : 1254 -1260.
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