原发性胃肠道T细胞淋巴瘤26例临床病理特征及预后分析

Clinicopathological Features and Prognostic Analysis of 26 Patients with Primary Gastrointestinal T Cell Lymphoma

目的:研究原发性胃肠道T细胞淋巴瘤临床病理特征及预后相关因素。方法:回顾性分析2008年1月至2013年12月期间我院收治的胃肠道T细胞淋巴瘤患者26例的临床资料。结果 :本组26例中,男∶女=1.17∶1,首发症状以消化道症状为主(42.3%),病变部位以肠道为主(73.1%)。患者3年生存率为15.4%,生存因素分析表明年龄、首发症状、病变直径、LDH升高与否、临床分期因素与预后相关(P<0.05)。结论:原发性胃肠道T细胞淋巴瘤是一组预后不良的疾病,其预后与年龄、首发症状、病变直径、LDH升高与否、临床分期因素等相关。

Objective：To investigate clinicopathological features and prognosis in patients with primary gastrointestinal T cell lymphoma. Methods：The clinical data of 26 patients with primary gastrointestinal T cell lymphoma were analyzed retrospectively from Jan 2008 to Dec 2013. Results：Among the 26 cases,the male/female ratio was 1.17：1, and the first syndrome was major in gastrointestinal discomfort. The intestine was the main location of lymphoma. The overall 3-year survival rate was 15.4%. And survival analysis resulted in that age,first syndrome, lesion size, LDH elevation, clinical stage could be its main prognostic factors. Conclusion： Primary gastrointestinal T cell lymphoma is a group of diseases with poor prognosis, and age, first syndrome,lesion size, LDH elevation, clinical stage could be its main prognostic factor.