经尿道等离子剜除术治疗良性前列腺增生的临床分析

Clinical analysis of transurethral plasma kinetics enucleation in the treatment of benign prostate hyperplasia

目的分析经尿道等离子前列腺剜除术在治疗良性前列腺增生中的临床应用效果。方法选取行经尿道等离子前列腺剜除术的良性前列腺增生患者26例,对其手术时间、术中出血量、切除组织量进行记录,术后3个月随访,比较手术前后的国际前列腺症状评分(IPSS)、生活质量评分(QOL)、残余尿量(RU)、最大尿流率(Qmax)等指标,评价其临床疗效,并记录治疗过程中的不良事件。结果术中平均切除组织量、术中出血量、手术时间,分别为(46.77±13.58)g、(17.46±8.22)g·L-1、(89.31±21.67)min;术后IPSS评分、QOL评分、平均Qmax与平均RU,分别是(10.65±3.059)分、(1.23±0.815)分、(19.31±3.782)m L·s-1、(18.54±21.39)m L。术后各项观察指标与术前比较,差异均有统计学意义(P<0.05);术后常见的并发症是包膜穿孔、尿道狭窄、再次出血。结论经尿道等离子前列腺剜除术在治疗良性前列腺增生中是安全有效的,值得临床推广应用。

Objective To analyze the clinical efficacy of transurethral plasma kinetic enucleation of prostate （PKEP） in the treatment of benign prostate hyperplasia. Methods The clinical data of 26 cases with BPH treated with PKEP were analyzed. The opera- tion time, bleeding, resected tissue weight of prostate,adverse events during the treatment were recorded. After 3 months follow - up, the clinical efficacy by compare the date before and after operation, included the international prostate symptom score （IPSS）, quality of life score （QOL） , post void residual （PVR） and maximum flow rate （Qmax） was evaluated. Results The average resected tissue weight of prostate ,bleeding,operation time were respectively（46.77 ± 13.58 ） g, （ 17.46 ±8.22） g · L^- 1, （ 89.31±21.67 ） min. The IPSS, QOL, Qmax and PVR were respectively 10.65 ± 3. 059,1.23 ± 0.815, （ 19.31 ± 3. 782 ） mL· s^ -I, （ 18.54 ±21.39 ） mL. IPSS, QOL, PVR and Qmax were significant improved in the patients after the operation （ P 〈0. 05 ）. The common complications were capsular perforation, ure- thral stricture and secondary bleeding. Conclusion PKEP is an effective and safe therapy in the treatment of BPH.