摘要
探讨右美托咪定经鼻腔黏膜给药全麻诱导方式在小儿手术中的应用效果。选择全麻手术患儿120例,据右美托咪定用量,采用随机数字表法分为:4μg/kg、6μg/kg、8μg/kg、10μg/kg组,每组各30例。术前30min将右美托咪定快速注入鼻腔,每侧各半量。采用Berggen、Riker方法评价效果并观察术后有无"迟延模仿"及行为异常发生。结果显示:10μg/kg组镇静效果最好,躁动发生例数、"迟延模仿"与行为异常的发生例数明显少于其他三组(P<0.05)。右美托咪定经鼻腔黏膜给药的麻醉诱导方式,患儿镇静效果良好,可减少患儿术后躁动及行为异常的发生,益于儿童健康发育。
This article is to investigate the effects of general anesthesia induction mode by dexmedetomidine delivered through nasal cavity .120 children undergoing general anesthesia ,scheduled for 4 groups （n= 30）：4mg/kg ,6mg/kg , 8mg/kg and 10mg/kg .The dexmedetomidine was delivered quickly into nasal cavity with the same dose each side ,30 min before operation .Berggen and Riker methods were used to value the effects .The time of each group children from the medicine used to sleeping and sedation were recorded .To investigate the ＂lated imitation＂ phenomenon and abnormal behavior occurred or no after operation .The results indicated that the sedative effect of 10mg/kg group was the best ;＂deferred imitation＂and＂abnormal behavior＂occurred were less than that in the rest （P〈0 .05） .The general anesthesia induction mode of dexmedetomidine delivered through nasal cavity had well sedation ,decrease the occurrence of ＂abnormal behavior＂were decreased ,and benefited children＇s health .
出处
《医学与哲学（B）》
2015年第5期58-60,90,共4页
Medicine & Philosophy(B)
关键词
右美托咪定
鼻腔
儿童
dexmedetomidine
nasal cavity
children
