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CBP治疗严重烧伤合并SIRS的临床研究

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摘要 目的通过临床连续血液净化治疗方法(Continuous blood purification,CBP)应用于严重烧伤并发发生全身炎症反应综合征(Systemic Inflammatory Response Syndrome,SIRS)的患者,探讨CBP对严重烧伤合并SIRS患者临床疗效,及其有效性,安全性。方法选择本院严重烧伤80例患者,随机分组,经CBP治疗后,通过与对照组在患者的生命体征;实验室检查;白介素8(Interleukin-8 IL-8),肿瘤坏死因子α(Tumor Necrosis Factor TNF-α)指标,转归进行比较,探讨临床疗效。结果 CBP治疗能降低严重烧伤合并SIRS患者的TNF-α、IL-8细胞因子水平。生命体征、实验室检查指标(血钠、血白细胞、血肌酐、血尿素氮、血氧分压)均有明显改善。继发多器官功能障碍综合征及死亡率明显下降。结论 CBP改善了严重烧伤合并SIRS患者的预后。
机构地区 内蒙古包钢医院
出处 《疾病监测与控制》 2015年第6期420-422,共3页 Journal of Diseases Monitor and Control
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