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Cripto-1在人肺癌组织中的表达及临床意义 被引量:2

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摘要 目的:探讨Cripto-1蛋白在人肺癌组织中的表达及其临床意义。方法:通过免疫组织化学方法检测60例肺癌患者的肺癌组织及50例癌旁组织中Cripto-1的表达,分析Cripto-1在人肺癌组织中的表达与临床的关系。结果:Cripto-1蛋白在人肺癌组织中的阳性表达明显高于癌旁组织(P<0.05);Cripto-1在人肺癌中的表达与患者的年龄和性别无明显相关(P>0.05),但与淋巴结转移、远处转移、侵袭范围及临床分期显著相关(P<0.05)。结论:Cripto-1可能在人肺癌的发生、发展、侵袭和转移过程中有重要作用,检测人肺癌组织中Cripto-1表达水平可能为肺癌的早期诊断提供依据,对肺癌的恶性程度评估及预后判断有一定参考价值。
出处 《中国民康医学》 2015年第12期74-75,共2页 Medical Journal of Chinese People’s Health
关键词 Cripto-1 肺癌
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参考文献4

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