亚麻醉剂量氯胺酮——芬太尼辅助小儿区域麻醉的临床分析

Analysis of Subanesthestic Dosage of Ketamine-Fentanyl Assisted Regional Anesthesia in Children

目的观察亚麻醉剂量氯胺酮联合芬太尼辅助小儿区域麻醉中的效果。方法将96例手术患儿随机分为两组,对照组采用氯胺酮麻醉,观察组采用亚麻醉剂量氯胺酮-芬太尼麻醉。结果观察组苏醒时间、氯胺酮用量均少于对照组,精神异常、躁动、呼吸抑制、肠胃道反应等不良反应发生率低于对照组,P<0.05,差异具有统计学意义。与术前相比,两组术后心率、血氧饱和度及平均动脉压三项指标均有变化,且观察组变化幅度小于对照组,P<0.05,差异具有统计学意义。结论亚麻醉剂量氯胺酮-芬太尼在小儿区域麻醉中具有良好的辅助效果。

Objective Observation the effect on subanesthestic dosage of ketamine -fentanyl assisted regional anesthesia in children. Methods 96 patients divided into two groups randomly, control group adopt ketamine anesthesia, the observation group adopt subanesthestic dosage of ketamine-fentanyl. Results The recovery time, ketamine with volume less than the control group, psychosis, agitation, respiratory depression, gastrointestinal reactions and other adverse events was lower than the control group, P〈0.05, had difference statistically significance. Compared with the preoperative and postoperative heart rate, oxygen saturation, and mean arterial pressure of the three indicators have changed, and the change in the magnitude of the observation group than the control group, P〈0.05, had difference statistically signiifcance. Conclusion Subanesthestic dosage of ketamine–fentanyl has good effect on regional anesthesia in children.