期刊文献+

氯吡格雷治疗急性冠脉综合征的临床效果分析 被引量:2

Analysis Clinical Effect on Clopidogrel Treatment of Acute Coronary Syndrome
下载PDF
导出
摘要 目的研究氯吡格雷治疗急性冠脉综合症患者的临床疗效。方法选取我院收治的82例急性冠脉综合症患者的临床资料,根据数字随机分组法原则,将患者分为观察组与对照组,每组各41例。对照组采用阿司匹林治疗,观察组在对照组基础上采用氯吡格雷治疗,比较两组患者的临床疗效与治疗前后肌钙蛋白水平变化情况。结果观察组治疗总有效率为95.12%,对照组治疗总有效率为80.49%,P<0.05,差异具有统计学意义。结论氯吡格雷在急性冠脉综合症的治疗中有着较高的应用价值,可有效提升临床疗效,改善肌钙蛋白水平。 Objective To study the clinical effect on clopidogrel treatment the patients with acute coronary syndrome research. Methods Selected 82 cases with acute coronary syndrome clinical data in our hospital, according to the figures randomized law principles, divided into the observation groups and the control group, each group had 41 cases. the control group adopt aspirin treatment, the observed group basis on the control group were treated with clopidogrel group in the clinical effect of the two groups of patients with troponin levels before and after treatment. Results The observation group total effective rate was 95.12% , the control group the total effective rate was 80.49%, P〈0.05, had difference statistically signiifcance. Conclusion Clopidogrel has higher value in the treatment of acute coronary syndrome, which can improve the clinical efifcacy and the level of troponin.
作者 蔡英博
出处 《中国继续医学教育》 2015年第16期149-150,共2页 China Continuing Medical Education
关键词 氯吡格雷 急性冠脉综合症 治疗效果 Clopidogrel, Acute coronary syndrome, Treatment effect
  • 相关文献

参考文献3

二级参考文献29

  • 1刘新兵,黄红漫,曹国良,周明成,许其倓.阿托伐他汀联合氯吡格雷对急性冠脉综合征血小板聚集率的影响[J].心血管康复医学杂志,2007,16(1):52-55. 被引量:7
  • 2柯元南,陈纪林.不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,35(4):295-304. 被引量:2143
  • 3Mehta SR, Yusuf S, Peters R J, et al. Effects of pretreatment with Clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study [ J ]. Lancet, 2001,358 (9281 ) : 527-533.
  • 4Savi P, Pereillo JM, Uzabiaga MF, et al. Identification and biological activity of the active metabolite of Clopidogrel [J]. Thromb Haemost, 2000,84 (5) : 891-896.
  • 5Steinhubl SR, Berger PB, Mann JT 3rd, et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial [J]. JAMA, 2002,228(19) :2411-2420.
  • 6Matetzky S, Shenkman B, Guetta V, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction[J]. Circulation, 2004,109(25) :3171-3175.
  • 7Khambekar SK, Kovac J, Gershlick AH. et al. Clopidogrel induced urticarial rash in a patient with left main stem percutaneous coronary intervention: Management issues [J]. Heart, 2004,90(3) :el4.
  • 8Fontana P, Dupont A, Gandrille S, et al. Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects [J]. Circulation, 2003,108(8) :989-995.
  • 9Wienbergen H, Gitt AK, Schiele R, et al. Comparison of clinical benefits of clopidogrel therapy in patients with acute coronary syndromes taking atorvastatin versus other statin therapies [ J ]. Am J Cardiol, 2003,92 ( 3 ) : 285-288.
  • 10Ray KK, Cannon CP, Ganz P. Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials? [ J ] Am J Cardiol, 2006,98 (11A) : 18P-25P.

共引文献47

同被引文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部