摘要
目的对卡马西平、托吡酯以及丙戊酸钠缓释片三种抗癫痫药用于脑炎继发癫痫中的疗效进行分析。方法将本院进行治疗的脑炎继发癫痫患者150例,随机将其分为A、B、C三组各50例,A组给予马西平进行治疗,B组给予托吡酯进行治疗,C组给予丙戊酸钠缓释片进行治疗,比较三组患者的临床治疗效果以及不良反应发生情况。结果三组相比,总有效率差异不显著(P>0.05);不良反应比较差异显著(P<0.05)。结论卡马西平、托吡酯以及丙戊酸钠缓释片治疗脑炎继发癫痫的效果相当,但托吡酯的不良反应率较低,更具有安全性。
Objective To analyze and investigate the safety and effectiveness of different antiepileptic drugs in the treatment of secondary epilepsy after viral encephalitis. Methods The hospital for treatment of 150 cases of secondary epilepsy after viral encephalitis patients, randomly divided into A, B, C three groups with 50 cases in each group, group A was given the carbamazepine treatment, group B was treated with topiramate for treatment, group C was treated with sodium valproate sustained release tablets for treatment, to compare the occurrence of three groups of patients with clinical curative effect and adverse reaction. Results The total efficiency of three groups compared, the difference was not significant（P〈0.05）, adverse reactions are significantly different（P〈0.05）. Conclusion Carbamazepine, topiramate and sodium valproate sustained release tablets in the treatment of epilepsy secondary to encephalitis effect, but the adverse effects of topiramate rate is low, so it has more security.
出处
《中国继续医学教育》
2015年第15期120-121,共2页
China Continuing Medical Education
