高渗盐水与甘露醇在恶性大脑中动脉脑梗死中的应用比较

Application Comparison of Hypertonic Saline and Mannitol in Malignant Middle Cerebral Artery Infarction

目的高渗盐水与甘露醇在恶性大脑中动脉脑梗死中的应用比较。方法 35例对照组采用甘露醇方法,35例观察组采用甘露醇和高渗盐水交替使用治疗。对比两组治疗结果及相关临床指标。结果对照组中血肌酐和尿素氮两者在浓度上有很明显的上升,观察组上升幅度小。观察组中肌酐和尿素氮在浓度上低于对照组(P<0.01)。结论交替使用高渗盐水和甘露醇可以在很大程度上提高动脉脑梗死患者的治疗效果,有很好的防止脱水的疗效。

Objective To compare the application of hypertonic saline and mannitol cerebral artery in malignant brain. Methods 35 patients in the control group were treated with mannitol method, 35 cases of observation group mannitol and hypertonic saline treatment used interchangeably. Compared two groups of treatment and clinical outcome indicators. Results The control group both in serum creatinine and blood urea nitrogen concentrations there was a clear increase in the magnitude of the rise in the observation group is very small. Observation group creatinine and blood urea nitrogen concentrations were significantly lower than in the control group（P〈0.01）. Conclusion The alternate use of hypertonic saline and mannitol can improve the treatment of patients with cerebral infarction in large arteries, have a good effect to prevent dehydration.