奥美拉唑与西米替丁治疗应激性胃溃疡的疗效对比分析

Efficacy Comparison of Omeprazole and Cimetidine in Treatment of Stress Ulcer

目的分析奥美拉唑与西米替丁治疗应激性胃溃疡的临床效果。方法将我院120例应激性胃溃疡患者随机分为60例观察组和60例对照组。对观察组采用奥美拉唑疗法,对照组则使用西米替丁进行治疗,对比两组疗效。结果观察组的胃液p H值为(6.71±0.19),对照组为(2.78±0.44),观察组高于对照组,且P<0.05;观察组胃泌素为(90.89±12.77)mg/L,对照组为(110.02±9.94)mg/L,对照组高于观察组,且P<0.05。观察组的总有效率为95.00%,对照组为70.00%,对照组低于观察组,且P<0.05。结论采用奥美拉唑治疗应激性胃溃疡能更为有效地改善患者胃部病症,缓解了患者的不适,疗效较为满意。

Objective Analysis of omeprazole and cimetidine clinical effects of stress ulcer. Methods Our hospital 120 cases of stress ulcer patients were randomly divided into 60 cases of observation group and 60 patients in the control group. Omeprazole therapy for the observation group, the control group using cimetidine treatment, comparing the two groups. Results p H value of gastric juice in the observation group（6.71 ± 0.19）, the control group（2.78 ± 0.44）, the observation group was significantly higher, and P〈0.05, gastrin observation group（90.89 ± 12.77）mg/L, the control group（110.02±9.94）mg/L, the control group was significantly higher than inthe observation group, and P〈0.05. The total effective rate of observation group 95.00%, 70.00% in the control group, the control group was significantly lower than in the observation group, and P〈0.05. Conclusion Omeprazole treatment of stress ulcer patients can be more effective in improving the stomach illness, alleviate patient discomfort, efficacy is satisfactory.