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西妥昔单抗致痤疮样皮疹68例临床预防性皮肤护理效果分析 被引量:3

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摘要 目的探讨西妥昔单抗致痤疮样皮疹患者采用预防性皮肤护理的临床效果。方法 68例西妥昔单抗致痤疮样皮疹患者,随机分为对照组和观察组,各34例,对照组实施常规护理,观察组在常规护理基础上实施预防性皮肤护理,比较两组的皮疹严重程度及护理效果。结果观察组的皮疹发生时间、持续时间及完成治疗周期数显著优于对照组,差异有统计学意义(P<0.05);观察组皮疹发生率低于对照组,差异有统计学意义(P<0.05)。结论对西妥昔单抗致痤疮样皮疹患者采用预防性皮肤护理的效果显著优于常规护理,缓解了皮疹严重程度,值得临床推广应用。
出处 《中国现代药物应用》 2015年第14期202-204,共3页 Chinese Journal of Modern Drug Application
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  • 1Rocha-Lima CM, Soares HP, Raez LE, et al. EGFR Targeting of Solid Tumors [ J ] . Cancer Control, 2007, lg ( 3 ) : 295-304.
  • 2Tscharner GG, Buhler S, Borner M, et al. Grover's disease induced by cetuximab [ J ] . Dermatology, 2006, 213 ( 1 ) : 37-39.
  • 3David E. Cetuximab in metastatic colorectal cancer[J] . LondonCancer New Drugs Group-APC/DTC Briefing, 2005, 7 ( 1 ) : 1-10.
  • 4Rhee J, Oishi K, Garey J, et al. Management of rash and other toxicities in patients treated with epidermal growth factor receptor targeted agents[J] . Clin Colorectal Cancer, 2005, 5 ( supple2 ) : S101-S106.
  • 5Harris M. Monoclonal antibodies as therapeutic agents for cancer[J]. Lancet Oncol, 2004, 5 ( 5 ) : 292-302.
  • 6David C, Yves H, Slvatore S, et al. Cetuximab monotherapy and cetuximab plus ifinotecan in irinotecanref ractory metastatic colorectal cancer[ J ] . New Engl J Med, 2006, 351 ( 4 ) : 337-345.
  • 7Chong G, Cunningham D. The role of cetuximab in the therapy of previously treated advanced colorectal cancer [ J ] . Semin Oncol, 2005, 32 ( 6 Suppl 9 ) : S55-58.
  • 8Harding J, Burtness B. Cetuximab : an epidermal growth factor receptor chemeric human-murine monoclonal antibody [ J ] . Drugs Today(Barc), 2005, 41 (2): 107-127.
  • 9Van Cutsem E, Lang I, DpHaens G, et al. KRAS status and efficacy in the first-line treatment of patients with metastatic colorectal cancer ( mCRC ) treated with FOLFIRI with or without cetuximab : The CRYSTAL experience [J]. J Clin Oncol, 2008, 26 : a2.
  • 10Bokemeyer C, Bondarenko I, Hartmann JT, et al. KRAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer ( mCRC )with FOLFOX with or without cetuximab : The OPUS experience [ J ] . J Clin Oncol, 2008, 26 : a4000.

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