以脾大为首发表现的恶性淋巴瘤的手术治疗

Operation Treatment of Malignant Lymphoma Presenting with Splenomegaly

目的探讨以脾大为首发表现的恶性淋巴瘤的手术治疗方法与预后。方法根据随机抽签方法将以脾大为首发表现的30例恶性淋巴瘤患者分为各15例的治疗组与对照组。两组都给予手术治疗,在此基础上治疗组在术后行辅助化疗,对两组生存率进行比较。结果所有患者完成治疗,术后随访6个月,治疗组和对照组的生存率分别为93.3%和66.7%,差异具有统计学意义(P<0.05)。结论以脾大为首发表现的恶性淋巴瘤的手术结合化疗能有效提高预后生存率,值得推广应用。

Objective To discuss prognosis and operation treatment of malignant lymphoma presenting with splenomegaly.MethodsAccording to random drawing method, 30 cases of malignant lymphoma patients presenting with splenomegaly divided into treatment group and control group, 15 cases in each group. Two groups were given operation treatment, on basis of operation treatment, treatment group received postoperative adjuvant chemotherapy. To compare survival rate of two groups.ResultsAl patients completed the treatment, after 6 months of folow-up, survival rate of treatment group and control group were respectively 93.3% and 66.7%, differences had statistical significance（P〈 0.05）.Conclusion Operation of malignant lymphoma presenting with splenomegaly combined with chemotherapy can improve the survival rate, it is worthy of popularization and application.