摘要
目的探讨甲状腺全切除术+中央区淋巴结清扫术在甲状腺乳头状癌中的临床效果。方法以我院578例甲状腺乳头状癌患者为研究对象,将其随机分成两组,对照组(289例)单独行甲状腺全切除术治疗,观察组(289例)选择甲状腺全切除术+中央区淋巴结清扫术治疗,比较两组的临床治疗效果。结果术后随访2年,观察组淋巴结复发转移率6.23%,对照组淋巴结复发转移率20.07%,组间比较差异具有统计学意义(χ2=24.24,P<0.01);观察组术后低钙血症和声带麻痹发生率为和16.61%和14.53%,对照组分别为11.07%和11.42%,均在2个月内恢复(P>0.05)。结论甲状腺全切除术+中央区淋巴结清扫术降低了甲状腺乳头状癌术后复发率,安全性良好,值得进步推广应用。
Objective To investigate clinical effect of total thyroidectomy＋central lymph node dissection in the treatment of papillary thyroid carcinoma. Methods 128 cases patients with papillary thyroid carcinoma were selected as research object. They were divided into two groups randomly. Control group（289 cases）was treated with total thyroidectomy. Observation group（289 cases）was treated with total thyroidectomy ＋ central lymph node dissection. The clinical effect was then compared. Results After 2 years followed-up, lymph node recurrence rate of observation group was 6.23%, and lymph node recurrence rate of control group was 20.07%. The difference had statistical significance（χ2 =24.24, P〈0.01）. The incidence of hypocalcemia and vocal cord paralysis of observation group were 16.61% and 14.53%, and the control group were 11.07% and 11.42%. The symptoms restored within two months. The difference had no statistical significance（P〈0.05）. Conclusion Total thyroidectomy＋central lymph node dissection reduces the recurrence rate of papillary thyroid cancer. It has a good safety, which is worthy of application.
出处
《中国医药指南》
2015年第13期36-37,共2页
Guide of China Medicine
