CT肺动脉栓塞指数与危险分层的相关性分析

Correlation between CT pulmonary embolism index and risk stratification in acute pulmonary embolism patient

目的:探讨急性肺栓塞患者CT肺动脉栓塞指数与危险分层的相关性。方法:纳入72例连续收治的急性肺栓塞患者,均经CT肺动脉造影确诊。按指南对患者进行危险分层并计算CT肺动脉栓塞指数,用Spearman法计算CT肺动脉栓塞指数与急性肺栓塞危险分层的相关系数,用受试者工作特征曲线评估CT肺动脉栓塞指数对每个危险分层的预测效能。结果:在72例急性肺栓塞患者中,低危组32例、中危组31例、高危组9例,三组CT肺动脉栓塞指数分别为(26.2±16.4)%、(52.9±10.6)%和(85.6±5.4)%,CT肺动脉栓塞指数与急性肺栓塞危险分层的相关系数为0.881(P<0.01)。肺栓塞指数对危险分层中的高危组预测效能最高,敏感性为66.7%,特异性为90.5%,曲线下面积达0.929(P<0.01)。结论:急性肺栓塞患者CT肺动脉栓塞指数与危险分层呈显著正相关。

Objective： To evaluate the correlation of CT pulmonary embolism Index （CTI） with risk stratification in patients with acute pulmonary embolism （APE）. Methods ： A total of 72 consecutive patients with APE selected in the study were categorized into three groups according to the guideline. CTI were calculat- ed with computerized tomography pulmonary angiography （CTPA）. The relationship of CTI and risk stratifica- tion of APE was analyzed by Spearman rank correlation test. The prediction power of CTI for each risk stratifica- tion of APE was tested with the area Under the receiver-operating characteristic （ROC） curve. Results：The CTI values of low-risk group （ n = 32）, intermediate-risk group （ n = 31 ） and high-risk group （ n = 9） were （ 26. 2 ± 16.4）%, （52. 9 ± 10. 6）%, （85.6 ± 5.4）%, respectively. Spearman coefficient of rank correlation be- tween CTI and risk stratification of APE was 0. 881 （P 〈0. 01 ）. Among the three groups, CTI had the stron- gest prediction power for the high-risk group （ area under the curve 0. 929, P 〈 0. 01 ） with a sensitivity of 66. 7% and a specificity of 90. 5%. Conclusions CT pulmonary embolism Index has a significant correlation with risk stratification in patients with acute pulmonary embolism.