无症状前列腺炎在中国男性的患病率及其危险因素(附编者按)

Prevalence and risk factors for asymptomatic prostatitis in Chinese men

目的 前列腺炎是困扰男性健康的常见疾病,尽管有诸多关于症状性前列腺炎的研究报道,但是对于无症状前列腺炎的研究却十分有限.因此本研究旨在通过一项横断面调查来探究无症状前列腺炎的患病率及其发病危险因素.方法 通过调查统计2012年6月至2012年12月在玉林市第一人民医院健康体检的成年男性,最终纳入1531例.对这些男性进行问卷调查,调查表包括社会人口学资料和生活方式特点.静脉血测定生化等指标.无症状前列腺炎根据美国国立卫生研究院慢性前列腺炎症状指数（NIH-CPSI）来界定,取前列腺按摩液测定白细胞计数结果.采用SPSS 13.0软件进行数据处理和分析.结果 我们的研究显示无症状前列腺炎的患病率为9.5％.进一步分析相关因素（年龄、肥胖、高血压、高血糖、脂代谢紊乱、吸烟、饮酒和体育运动）,结果提示年龄（OR=1.809;95％CI=1.277-2.564）是无症状前列腺炎发生的一个明显的危险因素,此外,饮酒者中无症状前列腺炎发生也明显增加（OR=2.026;95％CI=1.326-3.095）.而体育运动则能减少无症状前列腺炎的发生（OR=0.484;95％CI=0.343-0.685）,其他因素未显示与无症状前列腺炎有显著的关联.结论 无症状前列腺炎在中国男性人群有着较高的患病率,年龄和饮酒是增加该疾病发生的两个显著危险因素,而体育运动则是其保护因素.无症状前列腺炎应该引起重视.

Objective Prostatitis is a common health problem affecting the male population.Although symptomatic prostatitis has.been well known, asymptomatic prostatitis remains laregely known. Here, we used a cross-sectional study to investigate the prevalence and risk factors of asymptomatic prostatitis. Methods Data of normal males were collected from the First People＇s Hospital of Yulin from June 2012 to November 2012 and total of 1531 subjects were included in the study. A face-to-face interview was conducted to get the basic information of participants. Data of demographic characteristics and lifestyle characteristics were collected using a standardized questionnaire. Venous blood samples were collected for measuring biochemical parameters, etc. Asymptomatic prostatitis was defined by the National Institutes of Health Chronic Prostatitis Symptom Index （NIH-CPSI）. Meanwhile, EPS specimens and their leukocyte count were collected. The Data management and statistical analyses were performed using SPSS 13.0. Results Prevalence of asymptomatic prostatitis was 9.5% in our present survey. Among these potential risk factors such as age, obesity, smoking habits, alcohol drinking habits, physical activity, hypertension, dyslipidemia, and diabetes, age showed to be a significant risk factor for asymptomatic prostatitis （OR=1.809; 95%CI=1.277-2.564） and the risk ofNIH-IV prostatitis was significantly higher in alcohol drinkersthan non- drinkers （OR=2.026; 95%CI=1.326-3.095）. Physical activity was found to reduce the occurrence of asymptomatic prostatitis （OR=0.484; 95%CI=0.343-0.685）. However, other factors had no significant correlation to asymptomatic prostatitis. Conclusion Our findings indicate that asymptomatic prostatitis is prevalent in Chinese men. Age and alcohol drinking were risk factors for asymptomatic prostatitis, but physical activity was a protective factor. Asymptomatic prostatitis draws our attentions in future study.