连续性肾脏替代疗法对急性肾损伤的临床效果研究

Clinical Study on Continuous Renal Replacement Therapy for Acute Kidney Injury

目的：观察连续性肾脏替代疗法（CRRT）在治疗急性肾损伤（AKI）时的临床效果。方法：选取我院自2012年1月~2013年1月因急性肾损伤而即将准备接受治疗的52例患者作为研究对象,按照普通组26例,研究组26例的分配方法,将两组患者在接受治疗前的动脉压、呼吸、心率以及体温、经皮血氧饱和度、血清肌酐、尿素氮、APACHEⅡ分值进行对比统计。经过2周的不同疗法治疗后,再将两组患者的各项指标进行二次比对。结果：治疗前两组患者均出现心率、体温、血清肌酐、尿素氮升高的现象,动脉压、呼吸全部发生异常状况。经过2周的治疗,研究组26例患者除8例外,其余指标全部低于治疗前,病情呈好转趋势;普通组除心率、体温、血清肌酐、尿素氮明显下降外,其余指标反倒继续增长,2周内有15例死亡。研究组的所有患者平均APACHEⅡ分值均比普通组患者低出许多。结论：CRRT疗法在治疗急性肾损伤时有明显的临床效果,不但容易使患者的各项指标快速趋于平稳,且最终存活率高。

Objective： Observation of continuous renal replacement therapy（CRRT） in the treatment of acute kidney injury（AKI） in clinical effect.Methods：Select our hospital from January 2012-January 2013 will soon be treated for acute kidney injury in the 52 cases patients as the research object,according to the general group of 26 cases,26 cases of allocation methods of the,the two groups of patients before treatment of arterial pressure,respiration,heart rate and body temperature,transcutaneous oxygen saturation,blood urea nitrogen,serum creatinine,APACHE Ⅱ scores compare statistics.After two weeks of different therapy,then each index of two groups of patients were secondary.Results：Two groups of patients before treatment in both the heart rate,body temperature,the phenomenon of elevated serum creatinine and urea nitrogen,arterial pressure,and breathing all abnormal situation happened.After two weeks of treatment,the team of 26 patients except 8 exceptions,all the rest of the index is lower than before treatment,the disease showed a trend of improvement;Normal group in addition to heart rate,body temperature,serum creatinine and urea nitrogen decreased obviously,but the rest of the indicators continue to grow,two weeks,there were 15 people were killed.All patients with an average APACHEⅡ scores in the study group were much lower than normal group.Conclusion：CRRT therapy in the treatment of acute kidney injury has obvious clinical effect,not only easy to make patients quickly leveled off the indicators,and ultimately survival rate is high,suitable for everyday applications.