老年糖尿病患者口服降糖药物用药依从性的影响因素分析

Analysis of Influence Factors of Oral Hypoglycemic Drug Medication Ccompliance in Elderly Diabetic Patients

目的：研究老年糖尿病患者口服降糖药物用药依从性的影响因素。方法：将2011年3月~2013年5月期间在我院就诊的2型糖尿病患者纳入研究,调查患者的口服降糖药物用药依从性并分析影响因素。结果：（1）入组680例患者中,不完全依从268例,不完全依从率39.42%;（2）不同性别、年龄的患者,用药不完全依从率的差异无统计学意义（P〉0.05）;不同文化程度、BMI指数、吸烟、饮酒、医患关系、用药种类、用药频次、对疾病的认识、对药物的认识、家庭支持程度、医疗费用和家庭月收入的患者,用药不完全依从率的差异有统计学意义（P〈0.05）;（3）文化程度高、医患关系好、对疾病了解、对药物了解、家庭支持良好、家庭月收入高是用药依从性的保护因素（OR〉1）;BMI指数高、吸烟、饮酒、用药种类多、用药频次多、自费医疗是用药依从性的危险因素（OR〈1）。结论：文化程度、肥胖程度、吸烟和饮酒史、医患关系、用药情况、医疗知识、家庭情况、经济情况是口服降糖药物用药依从性的影响因素,在临床治疗的实践中应及时筛选可能出现治疗依从性不佳的高风险患者并给予干预措施。

Objective： To study the influencing factors of oral hypoglycemic medication compliance in elderly diabetic patients.Methods：Elderly diabetic patients in our hospital from March,2011 to May 2013 were enrolled and compliance condition as well as its related factors were investigated.Results：（1）680 cases were enrolled,incomplete compliance cases were 268 and incomplete compliance rate was 39.42%;（2）There was no significant difference in patients with different gender and age（P〉0.05）;there were significant difference on incomplete compliance rate in patients with different cultural level,BMI index,smoking,drinking,doctor-patient relationship,drug category,medication frequency,knowledge of disease,knowledge of drug,family support degree,medical fees and monthly family income（P〈0.05）;（3）High culture degree,good doctor-patient relationship,understanding of disease,understanding of drug,good family support,high family monthly income were protective factors on drug compliance （OR1） ;high BMI index, smoking,dr inking,high drug variety,high medication frequency,self-funded medical treatment were risk factors on drug compliance（OR1）.Conclusion： Cultural level,degree of obesity,smoking and drinking history,doctors-patients relationship,medication condition,medical knowledge,family situation,economicsituation are influence factors of oral hypoglycemic medication compliance in elderly diabetic patients;in the practice of clinical treatment,we should screen high risk patients those who may be poor compliance and give interventionin.