1149例眼科白内障手术预防使用抗菌药物情况分析

Analysis of 1 149 cases of antimicrobial prophylaxisin ophthalmology cataract surgery

目的:了解西京医院眼科白内障手术围手术期应用抗菌药物情况及合理性。方法:抽取该院眼科2013年1―11月全部白内障手术患者围手术期抗菌药物应用进行回顾性研究。结果:1 149例手术患者抗菌药物应用率为40.7%;应用最多的药物为头孢唑啉占85.0%,其次为头孢硫脒占7.9%;给药时机:术前30 min^2 h给药占88.3%术中给药占8.9%,术后给药占2.8%;抗菌药物使用疗程:术前给药1次占67.09%,术后给药≤24 h占27.8%;术后给药24~48 h占4.7%。结论:I类清洁切口手术预防使用抗菌药物占比例偏高;抗菌药物选择基本合理;抗菌药物应用时机基本合理,使用疗程基本符合国家要求;但存在无适应证选用抗菌药物现象。

Objective： To understand the application and rationality of antimicrobial agents about in perioperative ophthalmology cataract surgery in a tertiary hospital. Methods： The application of all antimicrobial agents in perioperative Ophthalmology Cataract surgery which was extracted in the hospital from January to November in 2013 was studied retrospectively. Results： The rate of using antimicrobial agents was 40.7% of 1 149 cases in the surgeries . The most widely used drug was cefazolin which accounted for 85.0%. The followed drug was cefathiamidine for 7.9%. Administration time： Preoperative administrations performed in 30 min-2 h before surgeries accounted for 88.3%, in operation for 8.9%, and after surgery for 2.8%. The Antimicrobial drugs which were used for once before operation accounted for 67.09%. The administration rate was 27.8% when drugs used in less than 24h after surgery, and 4.7% in 24-48 h after operation. Conclusion： The proportion of prophylaxis was high in the Class I clean incision. The selection of antimicrobial drug was reasonable. The application time of antimicrobial drugs was reasonable and the use of medication met national requirements. But there were no indications use of antimicrobial drugs.