电针治疗围绝经期抑郁症临床观察

Clinical Observation of Electroacupuncture for Peri-menopausal Depression

目的观察电针治疗围绝经期抑郁症的临床疗效。方法将确诊为围绝经期抑郁症的患者随机分为关元组(n=30)和内关组(n=30),共同治疗1个月后观察其Hamilton抑郁量表评分、改良Kupperman评分及血浆ACTH、血清CORT水平,并进行比较。结果两组治疗后各项指标均有不同程度的下降,关元组与内关组相比,差异有统计学意义(P<0.05)。结论电针可有效调节围绝经期抑郁症患者的内分泌功能,改善临床症状,从而提高围绝经期抑郁症患者的机体代偿功能及生存质量,其中尤以关元组效果明显。

Objective To observe the clinical efficacy of electroacupuncture in treating peri-menopausal depression. Method Patients diagnosed with peri-menopausal depression were randomized into a Guanyuan （CV4） group （n=30） and a Neiguan （PC6） group （n=30）. After 1-month treatment, Hamilton Depression Scale （HAMD）, modified Kupperman index, plasm ACTH and serum CORT levels were observed and compared. Result After intervention, the observed indexes were decreased to different extents, and the between-group differences were statistically significant （P〈0.05）. Conclusion Electroacupuncture can effectively regulate the endocrine function ofperi-menopausal depression patients, improve symptoms, and thus enhance the compensatory function and the quality of life, and the Guanyuan group shows a more significant effect.