热敏灸热敏化大椎穴治疗神经根型颈椎病临床观察

Clinical Observations on Heat-sensitive Point Dazhui(GV14) Moxibustion for the Treatment of Cervical Spondylotic Radiculopathy

目的观察热敏灸热敏化大椎穴治疗神经根型颈椎病的临床疗效,并初步探讨其作用机制。方法将96例神经根型颈椎病患者分为热敏灸热敏化大椎穴组(观察组)30例、悬灸非热敏化大椎穴组(对照组)33例及药物组33例。观察组取热敏化大椎穴,行热敏灸治疗;对照组取非热敏化大椎穴,行悬灸治疗;药物组采用口服颈痛颗粒治疗。观察3组治疗15 d前后临床症状、血清超敏C-反应蛋白(Hs CRP)含量及血清白细胞介素-8(IL-8)含量变化情况。结果 3种治疗方法对神经根型颈椎病均有一定治疗作用,观察组疗效最优(P<0.05);3组治疗后血清Hs CRP及IL-8含量均较治疗前降低(P<0.05),观察组更低于对照组及药物组(P<0.05),对照组与药物组比较差异无统计学意义(P>0.05)。结论热敏灸热敏化大椎穴比悬灸非热敏化大椎穴、口服颈痛颗粒疗效优,该法为治疗神经根型颈椎病较为理想的治疗方法,其机制可能与治疗后病变部位炎症因子降低有关。

Objective To investigate the clinical efficacy of heat-sensitive point Dazhui（GV14） moxibustion in treating cervical spondylotic radiculopathy. Method Ninety-six patients with cervical spondylotic radiculopathy were randomly allocated to a heat-sensitive point Dazhui moxibustion （observation） group of 30 cases, a non-heat-sensitive point Dazhui suspended moxibustion （control） group of 33 cases and a medication group of 33 cases. The observation group received heat-sensitive point Dazhui moxibustion; the control group, non-heat-sensitive point Dazhui suspended moxibustion; the medication group, oral administration of Jingtong granules. The clinical symptoms were assessed and serum hypersensitive C-reactive protein （HsCRP） and intefleukin-8 （IL-8） were measured in the three groups before and after 15 days of treatment. Result All the three treatments had a certain effect on cervical spondylotic radiculopathy. The therapeutic effect was best in the observation group （P〈0.05）. After treatment, serum HsCRP and IL-8 contents decreased in all the three groups compared with before （P〈0.05）. They were even lower in the observation group than in the control and medication groups （P〈0.05） but had no statistically significant differences between the control and medication groups （P〉0.05）. Conclusion The therapeutic effect of heat-sensitive point Dazhui moxibustion is better than those of non-heat-sensitive point Dazhui suspended moxibustion and oral Jingtong granules. It is a more ideal way to treat cervical spondylotic radiculopathy. The mechanism of its action may be related to post-treatment decrease in inflammatory factors in the lesion.