697例血小板抗体检测结果

Analysis of results in detection of platelet antibody in 697 cases

目的:探讨血小板抗体阳性与性别、血型、输血次数和输注疗效的相关性。方法:采用简易致敏红细胞血小板血清学技术,对697例输注血小板制剂患者进行血小板抗体检测,并对检测结果统计分析。结果:697例患者中共检出血小板抗体阳性74例(10.62%);血小板抗体阳性与性别、血型无明显相关性,但与输血次数呈正比(P<0.01),并且血小板抗体阳性与输注效果间差异有统计学意义(P<0.01)。结论:输血等免疫因素刺激导致产生血小板抗体,输血次数越多,血小板抗体产生概率越大;血小板抗体阳性会直接影响血小板输注效果。为提高血小板输注效果,对血小板抗体阳性者应尽量进行配合性输注。

Objective：Study on the relationship between platelet antibody positive and gender,blood types,blood transfusion number and infusion efficacy.Method：Simplified sensitized erythrocyte platelet serology techniques have been adopted in our hospital,697 cases of patients with platelet transfusion were selected for the detection of platelet antibodies,and statistical analysis of test results.Result：697cases were detected positive platelet antibody in 74cases（10.62%）;platelet antibody positive and patient gender,blood type has no significant correlation（P〉0.05）,but was positively related to the number of blood transfusions（P〈0.01）,and,with the effect of transfusion of platelet antibody positive was statistically significant（P〈0.01）.Conclusion：Stimulate blood transfusion immunological factors are thought to be the cause of platelet antibody,the more the number of transfusions of platelet antibodies,the greater the probability;platelet antibody positive will directly influence the results of platelet transfusion.In order to improve the effectiveness of platelet transfusion,on platelet antibody positive should be carried out with the infusion.