期刊文献+

石墨烯纳米材料在药物释放和基因传递中的应用 被引量:1

Application of graphene-based nanomaterial in drug delivery and gene delivery
下载PDF
导出
摘要 石墨烯纳米材料由于其独特的结构和优良的机械、光学和电学性能,已经在物理、化学和材料科学等领域广泛应用。最新研究表明其特殊的属性可应用在生物医学领域的,综述了石墨烯纳米材料在生物医学领域如药物释放和基因传递中的应用,最后指出了石墨烯纳米材料在生物医学领域应用中目前存在的问题。 Graphene-based nanomaterials,due to their unique structure and excellent mechanical,optical and e-lectrical properties and have been widely exploited in physics,chemistry and materials science and other fields. Emerging trends show that their exceptional properties can be exploited for biomedical applications,especially in drug delivery and gene delivery.we will review recent advances in graphene-based nanomaterials for drug de-livery and gene delivery,finally the existing problems of the graphene nanomaterials in the biomedical field are pointed out.
出处 《功能材料》 EI CAS CSCD 北大核心 2015年第B06期22-24,29,共4页 Journal of Functional Materials
基金 国家自然科学基金资助项目(21401088) 云南省应用研究基础资助项目(KKSY201205025)上 大学生创新创业训练计划资助项目(201210674027) 昆明理工大学分析测试基金资助项目(20140838 20140812)
关键词 石墨烯基纳米材料 药物释放 基因传递 生物医学 graphene-based nanomaterials drug delivery gene delivery biomedical
  • 相关文献

参考文献27

  • 1Novoselov K S, Geim A K, Morozov S V, et al. Electric field effect in atomically thin carbon films[J]. Science, 2004,306 (5696) : 666-669.
  • 2Ma X, Tao H, Yang K, et al. A functionalized graphene oxide-iron oxide nanocomposite formagnetically targeted drug delivery, photothermal therapy, and magnetic reso nance imaging[J]. Nano Res, 2012, 5(3): 199-212.
  • 3Kim H, Lee D, Kim J, et al. Photothermally triggered cytosolic drug delivery via endosome disruption using a functionalized reduced graphene oxide [J]. ACS Nano, 2013, 7(8): 6735-6746.
  • 4Dembereldorj U, Kim M, Kim S, et al. A spatiotemporal anticancer drug release platform of PEGylated graphene oxide triggered by glutathione in vitro and in vivo[J]. J Mater Chem, 2012, 22: 23845-23851.
  • 5Wu J, Wang Y S, Yang X Y, et al. Graphene oxide used as a carrier for adriamycin can reverse drug resistance in breast cancer cells[J]. Nanotechnology, 2012, 23(35): 355101.
  • 6Bai H, Li C, Wang X, et al. A pH-sensitive graphene ox- ide composite hydrogeI[J]. Chem Commun, 2010, 46: 2376-2378.
  • 7Yang Xiaoying, Zhang Xiaoya, Liu Zunfeng, et al. High- efficiency loading and controlled release of doxorubicin hydrochloride on graphene oxide[J]. J Phys Chem C, 2008, 112(45) :17554-17558.
  • 8Depan D, Shah J, Misra R D K. Controlled release of drug from folate-decorated and graphene mediated drug delivery system: synthesis, loading efficiency, and drug release response[J]. Mater Sei Eng C, 2011, 31 (7): 1305-1312.
  • 9Pan Y, Bao H, Sahoo N G, et al.Water-soluble poly(N- isopropylacrylamide )-graphene sheets synthesized via click chemistry for drug delivery[J]. Adv Funct Mater, 2011, 21 (14): 2754-2763.
  • 10Wen H, Dong C, Dong H, et al. Engineered redomre sponsive PEG detachment mechanism in PEGylated nanographene oxide for intracellular drug delivery [J]. Small, 2012 ,8(5):760-769.

同被引文献1

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部