新生儿重症监护病房医院感染目标性监测分析

Targeted Surveillance of Nosocomial Infection in Neonatal Intensive Care Units

目的探讨目标性监测对新生儿重症监护病房(NICU)患儿实施目标性医院感染干预措施,分析医院感染的发生发展规律。方法根据2009年制订的《医院感染监测规范》中目标性监测方法,收集我院入住NICU患儿的感染监测数据,进行目标性的前瞻性监测,填写统一调查表。探究NICU医院感染发病率及感染部位分布状况,收集相应目标监测指标,并对监测结果进行统计学分析。结果目标性监测我院NICU收治危重患儿810例次,发生医院感染20例次(2.5%),干预期NICU医院感染发病率明显优于监测期,差异有统计学意义(P<0.05);此次医院感染的病原菌以肺炎克雷伯菌肺炎亚种(产超广谱β-内酰胺酶[ESBLs]的耐药表型)多见。结论医院感染在NICU中的危险因素较多,控制抗菌药物使用规范、严格执行操作流程、加强无菌消毒措施,对降低耐药菌感染及医院感染相对发病率有一定效果。

Objective To explore the target monitoring in neonatal intensive care unit（NICU）in children with interventions targeted hospital infection,hospital infection occurrence and development regularity analysis.Methods According to 2009 to develop a ＂hospital infection surveillance norms＂ target monitoring methods,our hospital to establish children in NICU infection surveillance logs,prospective monitoring of targets, Fill in uniform questionnaire. Explore the NICU incidence of nosocomial infection and the distribution of infection sites,develop appropriate monitoring program objectives,and monitoring results were analyzed statistically.Results Objective monitoring of NICU in our hospital treated 810 cases of critically ill children,nosocomial infection happened in 20 cases（2.5%）,stem morbidity is obviously better than expected NICU hospital infection monitoring period,the difference was statistically significant（P〈0.05）;pathogenic bacteria in the hospital infection with Klebsiella pneumoniae subspecies （resistance phenotype production extended spectrum beta lactamases[ESBLs]）see more.Conclusion NICU hospital infection risk factors are more standard use of antimicrobial drugs by controlUng,strict implementation of operational processes, strengthen aseptic measures to reduce drug-resistant infections and the relative incidence of nosocomial infection have a certain effect.