纤维支气管镜灌洗治疗昏迷患者合并重症肺部感染的疗效观察

Efficacy of Bronchoscopy Lavage in Coma Patients with Severe Pulmonary Infection

目的:探讨纤维支气管镜灌洗治疗昏迷患者合并重症肺部感染的临床疗效。方法:50例昏迷合并重症肺部感染患者随机分为两组,对照组予抗感染等常规治疗,观察组在此基础上联合应用纤维支气管镜灌洗治疗,比较两组患者临床疗效。结果:观察组治疗总有效率为88%,明显高于对照组的64%,差异有统计学意义(P<0.05);观察组患者临床指标包括体温、血象恢复正常时间、肺部症状消失时间、机械通气时间、住院时间等均明显短于对照组,差异有统计学意义(P<0.05)。结论:在抗感染等常规治疗的基础上采用纤维支气管镜灌洗治疗昏迷合并重症肺部感染可提高临床疗效,并使肺部感染得到有效控制。

Objective： To investigate the clinical efficacy of bronchoscopy lavage in coma patients with severe pulmonary infection. Method： 50 coma patients with severe pulmonary infection were randomly divided into two groups,the control group was treated with conventional anti-infection treatment,the observation group combined with bronchoscopy lavage treatment on that basis,the clinical efficacy were compared between the two groups. Result： The total effective rate in the observation group was 88%,and it was significantly higher than the control group（ 64%）,the difference was statistically significant（ P〈0.05）; the time of body temperature,WBC returned to normal,pulmonary symptoms disappear time,mechanical ventilation time,hospital days in the observation group were significantly shorter than those in the control group,the difference was statistically significant（ P〈0. 05）. Conclusion： On the basis of anti- infective therapy,the bronchoscopy lavage in coma patients with severe pulmonary infection can improve clinical outcomes,and can control lung infection effectively.