癫痫持续状态相关危险因素分析

The related influencing factors of status epilepticus

目的探讨癫痫持续状态(SE)的相关危险因素情况。方法选取亳州市人民医院收治的129例癫痫患者,将79例SE患者作为SE组,未发生SE的50例患者作为对照组。回顾分析两组患者一般资料,同时分析两组患者颅脑损伤、病毒性脑炎急性期、脑血管病等情况,对SE的影响因素进行统计分析。结果两组患者颅脑损伤、病毒性脑炎急性期、脑血管病、不规则服药差异有统计学意义(P<0.05),两组患者家族史、脑皮质发育异常、CO中毒或者酒精中毒、颅内占位病变、发热、脑血管畸形差异无统计学意义(P>0.05)。通过logistic回归分析,颅脑损伤、病毒性脑炎急性期、脑血管病、不规则服药为SE的独立危险因素(P<0.05)。结论颅脑损伤、病毒性脑炎急性期、脑血管病、不规则服药是SE发生的危险因素,及时规避SE的相关危险因素,对于临床治疗和提高预后均有重要意义。

Objective To approach the related influencing factors of status epilepticus（ SE） . Methods The clinical data of 79 ca-ses of SE patients in our hospital were analysed, then patients without SE were selected as control group, then the influence of brain injury, acute viral encephalitis, stroke on SE was analysed. Results The difference in brain injury, acute viral encephalitis, stroke, irregular medi-cation of the two groups had statistical significance（P〈0. 05）, while correlative factors like family history, cerebral cortical dysplasia, car-bon monoxide poisoning or alcoholism, intracranial lesions occupied, fever, cerebrovascular malformation of the two groups showed no differ-ence（P〉0. 05）. Based on logistic regression analysis, brain injury, acute viral encephalitis, stroke, and irregular medication were inde-pendent risk factors of SE （P〈0. 05）. Conclusion Brain injury, acute viral encephalitis, stroke, irregular medication are independent risk factors of SE patients. Timely avoiding related influencing factors of SE is important in clinical treatment and improvement of the prognosis.