肉苁蓉汤联合PPDO微创埋线治疗老年顽固性便秘临床研究

Clinical observation of Roucongrong decoction combined with PPDO minimally invasive embedded wire′s on elderly stubborn constipation

[目的]观察肉苁蓉汤联合聚对二氧六环酮(PPDO)微创埋线治疗老年顽固性便秘的疗效。[方法]将入选病例按随机数字表法随机分为治疗组及对照组,每组40例。对照组口服果导片治疗。治疗组采用肉苁蓉汤联合PPDO微创埋线。两组疗程均为4周。[结果]治疗后各时间点的临床疗效呈逐渐递增趋势;患者治疗前后在排便间隔时间、粪便性质、排便费力均有明显改善,差异有统计学意义(P<0.05);治疗组与对照组比较,差异有统计学意义(P<0.05);治疗后两组48 h和72 h残留标记物数目与治疗前相比均显著降低(P<0.05)。[结论]肉苁蓉汤联合PPDO微创埋线治疗老年顽固性便秘明显改善临床症状,增强胃肠动力。

[Objective] To observe the clinical observation of Roucongrong decoction combined with PPDO minimally invasive embedded wire′ s on elderly stubborn constipation. [Methods] The cases selected by random method were divided into the treatment group and control group, 40 cases in each group. The control group was treated by oral Guodao tablet. Treatment group was treated by Roucongrong decoction combined with PPDO minimally invasive embedded wire. Course of treatment of two groups were 4 weeks. [Results] After treatment the clinical curative effect was gradually increasing of each point. Patients in defecation time interval, stool properties,defecate effort had improved significantly before and after treatment, with statistical significance（P〈0.05）;Compared with control group, treatment group was statistically significant（P〈0.05）. In the two groups after treatment, 48 h and 72 h residual marker number compared with before treatment were significantly lower（P〈0.05）. [Conclusion] Roucongrong decoction combined with PPDO minimally invasive embedded wire can obviously improve clinical symptoms, enhance the gastrointestinal dynamics.