早期使用人血清蛋白治疗高危新生儿的疗效观察

Clinical effect of early application of the human albumin in treating high-risk newborns

目的探讨早期使用人血清蛋白治疗高危新生儿的疗效。方法选取2012年3月—2013年9月出生的高危新生儿49例,随机分为干预组(25例)与对照组(24例)。对照组予以常规治疗,干预组在对照组基础上早期使用人血清蛋白治疗。观察两组患儿并发症发生情况、并发症持续时间及住院时间。结果干预组患儿硬肿、黄疸、肺炎、缺血缺氧性脑病、败血症发生率低于对照组,差异有统计学意义(P<0.05);干预组患儿硬肿、黄疸、肺炎、败血症持续时间及住院时间短于对照组(P<0.05)。结论早期使用人血清蛋白治疗高危新生儿的疗效显著,并发症少,有利于患儿康复。

Objective To study clinical effect of early application of the human albumin in treating high-zisk newbo-rns. Methods A total of 49 high-risk newborns were selected in the First People＆#39;s Hospital of Lanzhou from March 2012 to September 2013,they were randomly divided into intervention group（25 cases）and control group（24 cases）. Control group were treated with conventional treatment,intervention group were treated with early application of the human albumin on the basis of control group. Occurrence of complications,complications duration time and hospital stays between the two groups were com-pared. Results Scleredema, jaundice, pneumonia, hypoxic ischemic encephalopathy and septicemia rate of intervention group were lower than control group（P〈0. 05）,Scleredema,jaundice,pneumonia,hypoxic ischemic encephalopathy and septicemia duration time and hospital stays of intervention group were shorter than control group（P〈0. 05）. Conclusion Ear-ly application of the human albumin has notable curative effect in the treatment of high-risk newborns,has less complications and is helpful to children＆#39;s rehabilitation.