探讨黄体酮治疗黄体功能不全所致先兆流产的临床疗效

目的：探究并分析黄体酮治疗黄体功能不全所致先兆流产的临床疗效及其安全性,探讨其临床适用性。方法：病例选择从2014年1月上旬～2014年12月下旬于我院接受治疗的78例因黄体功能不全所致先兆流产的患者,简单随机分为试验组和对照组,对照组应用保胎灵胶囊进行治疗,试验组在常规治疗的基础上联合黄体酮治疗。观察治疗过程中两组患者的临床疗效及不良反应情况。结果：治疗后试验组患者的总有效率为97.1%,而对照组为76.5%,差异有统计学意义（X2=6.2750,P=0.0122）,试验组患者不良反应发生率为8.8%,对照组患者为5.9%,差异无统计学意义（X2=0.2159,P=0.6422）。试验组治疗后β-人绒毛膜促性腺激素（β-HCG）水平较治疗前有显著升高,与对照组相比较差异具有统计学意义。结论：黄体酮治疗黄体功能不全所致先兆流产临床疗效显著,且用药安全,适合临床长期推广应用。

Objective To study the clinical curative effect and safety of luteosterone to treating the threatening miscarriage caused by the incomplete function of pregnant women corpus luteum. Methods To divide the 78 cases randomly into two groups admitted in our hospital from January 2014 to December 2014 because of early threatening miscarriage caused by the incomplete function of pregnant women corpus luteum：the experimental group taking oral progestin capsule treatment, and the control group treated by Baotailing capsule. And observed the clinical effect and adverse reaction of two groups of patients after treatment. Results the total effective rate of the experimental group was 97.1% and it was 76.5% of the control group, between which there’s statistical significance.,the adverse reaction rate of the treatment group was 8.8% and it was 5.9% of the control group, between which there was no statistical significance, the level of β-HCG had significantly higher after treatment in the experimental group, there was no statistical significance between the two groups. Conclusion the clinical curative effect and safety of luteosterone to treating the threatening miscarriage caused by the incomplete function of pregnant women corpus luteum is remarkable ,worthy of clinical application.