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儿童哮喘发作病因分析 被引量:1

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摘要 目的:分析在本院治疗的哮喘患儿发病原因。方法:回顾性收集我院2009年5月~2014年5月共收治的哮喘患儿287例,调查其既往哮喘诊断情况,分析其发生哮喘的可能原因(家族史、过敏原、呼吸道感染)。结果:1家族哮喘史:287例患儿中,存在一级家族哮喘史97例,二级家族哮喘史64例。2过敏史:哮喘患儿中有过敏性鼻炎者151例,痒疹(包括湿疹、荨麻疹等)31例,树草花粉过敏者26例,药物过敏者9例,食物过敏35例。252例有过敏史的患儿中217例过敏源点刺实验阳性。3呼吸道感染:本次调查的287例哮喘患儿中197例患儿进行了呼吸道病原检测,发现其中存在呼吸道感染的患儿121例。以4岁为分界点分析发现,5~14岁的哮喘患儿其存在过敏史率明显高于0~4岁患儿(P〈0.05);同时,5~14岁患儿发病时呼吸道病原检测阳性率也高于0~4岁(P〈0.05)。仅家族史方面,不同年龄的患儿其分布相近(P〉0.05)。调查中有42例存在早产或出生低体重史儿童,此类儿童在过敏史及呼吸道感染史人数上均高于正常生产的儿童(P〈0.05),而家族史方面人数分布相近(P〉0.05)。结论:本次回顾性分析中患儿过敏史、家族史及呼吸道感染情况是患儿哮喘发作的主要病因,患儿年龄越大,越有可能是过敏史及呼吸道感染所致,对于年龄偏大儿童且存在过敏史及呼吸道感染,或伴有哮喘家族史者应予以关注。
机构地区 增城市新塘医院
出处 《北方药学》 2015年第7期170-171,共2页 Journal of North Pharmacy
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参考文献10

  • 1尚云晓.小儿重症哮喘的治疗[J].中国小儿急救医学,2006,13(6):503-506. 被引量:28
  • 2ChivuRD, Chivu LI,Iamandescu IB,et al. Asthma in childrenand adolescents:socio -economic and psycho -somatic considera-tions[J]. Pneumologia, 2007,56( 3 ) : 147-150.
  • 3WalkerHA, Chen E. The impact of family asthma managementon biology:a longitudinal investigation of youth with asthma[J].Be-hav Med,2010,3(4):326-334.
  • 4儿童支气管哮喘诊断与防治指南[J].中华儿科杂志,2008,46(10):745-753. 被引量:2510
  • 5杨磊,黄洋,周小勤,黄兆选.武汉地区儿童支气管哮喘患病率及危险因素调查[J].中华实用儿科临床杂志,2013,28(21):1622-1624. 被引量:44
  • 6AmreDK,Infante —Rivard C,Gautrin D,et al.Socioeconomicstatus and utilization of health care services among asthmatic chil-dren[J].J Asthma,2002,39(7):625-631.
  • 7HomerSD. Childhood Asthma in a rural environmentrimplica-tions for clinical nurse specialist practice [J].Clin Nurse Spec,2008,22(4):192-198.
  • 8StingoneJA, Claudio L.Disparities in the use of urgent healthcare services among asthmatic children[J].Ann Allergy Asthma Im-munol ,2006,97(2):244-450.
  • 9BouaheyHA, Sorkness CA, King TS, et al. Daily versus as-needed corticosteroids for mild persistent asthma [J]. N Engl JMed,2005,352(15):1519-1528.
  • 10BokhourBG1, Cohn ES,Cortes DE,rt al. Patterns of concor-dance and non -concordance with clinician recommendations andparents’ explanatory models in children with asthma[J].Patient E-duc Couns, 2008,70( 3) : 376-385.

二级参考文献26

  • 1尚云晓.小儿哮喘持续状态与急救[A].见:袁壮主编.儿科急重症与疑难病例诊治评述[C].北京:人民卫生出版社,2002.77.
  • 2尚云晓,译.变态反应性疾病.见魏克伦,主译.现代儿科疾病诊断与治疗第12版[M].北京:人民卫生出版社,1999.1014-1045.
  • 3Behrman RE,Kliegman PM,Jenson HB.Asthma treatment.In:Nelson textbook of pediatrics[M].16th Edition[M].Beijing:Science press,2001.664-679.
  • 4Afessa B,Morales I,Cury JD.Clinical course and outcome of patients admitted to an ICU for status asthmaticus[J].Chest,2001,120(5):1616-1621.
  • 5Villeneuve EJ,Zed PJ.Nebulized magnesium sulfate in the management of acute exacerbations of asthma[J].Ann Pharmacother,2006,40(6):1118-1124.
  • 6Rodrigo GJ,Rodrigo C.Intravenous montelukast in acute asthma[J].Am J Respir Crit Care Med,2004,169(1):130-131.
  • 7Holgate ST,Djukanovic R,Casale T,et al.Anti-immunoglobulin E treatment with omalizumab in allergic diseases:an update on anti-inflammatory activity and clinical efficacy[J].Clin Exp Allergy,2005,35(4):408-416.
  • 8Lazic N,Roberts G,Custovic A. Multiple atopy phenotypes and their associations with asthma:similar findings from two birth cohorts[J].{H}ALLERGY,2013,(06):764-670.
  • 9Pike KC,Inskip HM,Robinson SM. The relationship between maternal adiposity and infant weight gain,and childhood wheeze and atopy[J].{H}THORAX,2013,(04):372-379.
  • 10Garden FL,Simpson JM,Marks GB. Atopy phenotypes in the Childhood Asthma Prevention Study (CAPS) cohort and the relationship with allergic disease:clinical mechanisms in allergic disease[J].{H}Clinical and Experimental Allergy,2013,(06):633-641.

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