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儿童哮喘发作病因分析 被引量:1

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摘要 目的:分析在本院治疗的哮喘患儿发病原因。方法:回顾性收集我院2009年5月~2014年5月共收治的哮喘患儿287例,调查其既往哮喘诊断情况,分析其发生哮喘的可能原因(家族史、过敏原、呼吸道感染)。结果:1家族哮喘史:287例患儿中,存在一级家族哮喘史97例,二级家族哮喘史64例。2过敏史:哮喘患儿中有过敏性鼻炎者151例,痒疹(包括湿疹、荨麻疹等)31例,树草花粉过敏者26例,药物过敏者9例,食物过敏35例。252例有过敏史的患儿中217例过敏源点刺实验阳性。3呼吸道感染:本次调查的287例哮喘患儿中197例患儿进行了呼吸道病原检测,发现其中存在呼吸道感染的患儿121例。以4岁为分界点分析发现,5~14岁的哮喘患儿其存在过敏史率明显高于0~4岁患儿(P〈0.05);同时,5~14岁患儿发病时呼吸道病原检测阳性率也高于0~4岁(P〈0.05)。仅家族史方面,不同年龄的患儿其分布相近(P〉0.05)。调查中有42例存在早产或出生低体重史儿童,此类儿童在过敏史及呼吸道感染史人数上均高于正常生产的儿童(P〈0.05),而家族史方面人数分布相近(P〉0.05)。结论:本次回顾性分析中患儿过敏史、家族史及呼吸道感染情况是患儿哮喘发作的主要病因,患儿年龄越大,越有可能是过敏史及呼吸道感染所致,对于年龄偏大儿童且存在过敏史及呼吸道感染,或伴有哮喘家族史者应予以关注。
机构地区 增城市新塘医院
出处 《北方药学》 2015年第7期170-171,共2页 Journal of North Pharmacy
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参考文献10

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