茵栀黄颗粒治疗药物性肝病30例疗效观察

The Yinzhihuang Granula treatment of drug-induced liver disease clinical effects

目的观察茵栀黄颗粒治疗药物性肝病的临床效果。方法将自2013年1月开始入住我院的药物性肝病患者60例随机分为两组:对照组(30例)和治疗组(30例)。对照组给予常规治疗的保肝药物(如甘草酸二铵等),治疗组服用茵栀黄颗粒6g/次,每天3次,两组疗程均为8周。监测治疗前、4周、8周肝功能变化和观察临床疗效。结果治疗组在肝功能改善方面明显优于对照组(P<0.05)。结论茵栀黄颗粒治疗药物性肝病确有较好疗效。

Objectives To observe the Yinzhihuang Granula treatment of drug-induced liver disease clinical effects. Methods In our hospital 60 cases of drug-induced liver disease were randomly divided into control group （30 cases） and treatment group （30 cases） and control group received conventional therapy hepatoprotective drugs （such as glycyrrhizic acid, etc. ） , the treatment group with the Yinzhihuang Granula, were treated for eight weeks. Monitored before treatment, four weeks, eight weeks, and changes in liver function observed clinical efficacy. Results The results of liver function improved in the treatment group was superior to the control group （ P 〈 0. 01 ）, the treatment group and the control group, the clinical efficacy, the difference was statistically significant （ P 〈 0. 01 ）. Conclusions Yinzhihuang Granula treatment of drug-induced liver disease does have a good effect.