“从胃治咳”法治疗胃食管反流性咳嗽的临床观察

Effect of Treating Cough from Stomach in Gastroesophageal Reflux Cough: A Cbinical Obserration

目的观察并评价通降和胃方对胃食管反流性咳嗽患者生活质量的影响,探讨该方的临床应用价值。方法纳入70例GERC患者,将患者随机分为中药组35例(予通降和胃方)和西药组35例(予奥美拉唑联合莫沙必利),疗程8周,于治疗前后行SF-36评分,评价两组患者生活质量的变化。结果中药组、西药组SF-36中PCS随治疗时间的变化趋势差异无统计学意义(P>0.05),但中药组、西药组MCS变化趋势不同(P<0.01),中药组MCS改善程度大于西药组;中药组PCS、MCS治疗前后变化差异无统计学意义(P>0.05),西药组PCS、MCS治疗前后变化趋势不同,西药组PCS改善程度较明显(P<0.01)。结论通降和胃方能够在生理、心理维度提高患者的生活质量。

Objective To observe and evaluate the effects of Tongjiang Hewei Decoction on living quality of patients with gastroesophageal reflux cough（ GERC）,and explore its advantages in clinical application. Methods 70 patients with GERC were included in this research and they were randomly divided into traditional Chinese medicine（ TCM） group and western medicine（ WM）group（ n1 = n2 = 35）. The former was treated with Tongjiang Hewei Decoction. Meanwhile the latter was treated with Omeprazole and Mosa Billy. Both before and after the treatment course of 8 weeks,SF- 36 was needed to be completed to evaluate changes in living quality of 2 groups. Results In SF- 36,although there was no statistically significant difference between TCM group and WM group in the comparison of PCS throughout the whole course of treatment（ P〉0. 05）,TCM improved MCS more than WM（ P〈0. 01）. There was no statistically significant difference between PCS and MCS in the TCM group during the whole treatment course（ P〈0. 05）,while PCS increased more obviously than MCS in WM group（ P〈0. 01）. Conclusion Tongjiang Hewei Decoction can improve the living quality of patients with GERC in physiological and psychological aspects.