纳米碳甲状旁腺负显影技术在甲状腺癌根治术中的应用

Application of Nano-carbon Parathyroid Negative Imaging Technique to Radical Thyroidectomy for Thyroid Cancer

[目的]研究纳米碳甲状旁腺负显影技术在甲状腺癌根治术中的应用。[方法]分析118例甲状腺癌患者的临床资料,随机分为研究组(60例)和对照组(58例),研究组术中注射纳米碳混悬液。对两组患者的血钙、甲状旁腺素水平进行比较分析。[结果]研究组甲状旁腺误切率为1.7%,对照组为5.2%(P=0.587);一过性低钙血症发生率分别为3.3%和15.5%(P=0.023);永久性低钙血症发生率分别为0和1.7%(P=0.492);PTH暂时性减低发生率分别为3.3%和12.0%(P=0.140);PTH永久性减低发生率分别为0和1.7%低(P=0.492)。[结论 ]纳米碳甲状旁腺负显影技术在甲状腺癌根治术尤其双侧甲状腺全切除术中可有效保护甲状旁腺。

[Purpose] To investigate the application of nano-carbon parathyroid negative imaging technique to radical thyroidectomy for thyroid cancer. [Methods]The clinical data of 118 cases with thyroid cancer were analyzed,and patients were randomly divided into two groups,study group（n=60） and control group（n =58）. Patients in study group used nano-carbon solution. The blood calcium and parathyroid hormone levels between the two groups were compared. [Results]The mistakenly cutting rate of parathyroid of study group and control group was 1.7% and 5.2%（P=0.587）. The incidence of transient hypocalcemia in the 2 groups was 3.3% and 15.5%（P=0.023）respectively. The incidence of permanent hypocalcemia was 0 and 1.7%（P =0.492） respectively.The incidence of transient low PTH-emia was 3.3% and 12.0%（P=0.140）,and the incidence of permanent low PTH-emia was 0 and 1.7%（P =0.492） respectively. [Conclusion] Nano-carbon parathyroid negative imaging technique could protect parathyroid effectively in radical thyroidec-tomy especially in bilateral thyroidetomy.