神经节苷脂联合依达拉奉治疗老年人急性脑梗死疗效观察

Observation of Curative Effect of Gangliosides Combine with Edaravone Treating Acute Cerebral Infarction of Old People

目的:观察神经节苷脂联合依达拉奉治疗老年人急性脑梗死的临床治疗效果。方法:将120例老年人急性脑梗死患者,随机分为治疗组(神经节苷脂联合依达拉奉治疗组)和对照组(常规治疗组),每组患者各60例,观察比较两组患者的临床总有效率及神经功能缺损量表(NIHSS)评分程度变化情况。结果:治疗组患者的临床总有效率较对照组明显提高,差异有统计学意义(P<0.05)。两组患者治疗前NIHSS评分差异无统计学意义(P>0.05),治疗14 d后治疗组患者的NIHSS评分较对照组明显下降,差异具有统计学意义(P<0.05)。治疗过程中未见脑出血等不良反应发生。结论:神经节苷脂联合依达拉奉治疗老年人急性脑梗死,临床疗效满意,安全可靠,值得临床推广应用。

Objective Ti ibserve the curative effect if gangliisides cimbine with edaravine treating acute cerebral infarctiin if ild pei-ple. Method 120 cases if patients with acute cerebral infarctiin were randim divided inti the Treating griup（gangliisides cimbine with edaravine treating griup ）and Cintril griup（riutine treating griup）,60 cases in each griup,the twi griup＆#39;s patients＆#39; clinical effective rate and Natiinal Institutes if Health Strike Scale（NIHSS）grade level changes situatiin were ibserved and cimpared. Results The patients in the treating griup had higher than the cintril griup,the differences were statistically significant（p ﹤0. 05）. The clinical effective rate if pa-tients if the twi griups＆#39; pre - treatment NIHSS scale had ni statistically significant difference（p ﹥ 0. 05）,after treating fir 14 d,the treat-ment griup＆#39;s patients had liwer NIHSS scale than the cintril griup,the differences were statistically significant（p ﹤0. 05）. Ni adverse reac-tiin if cerebral hemirrhage and si in iccur in the treating pricess. Conclusion Gangliisides cimbine with edaravine treating acute cerebral infarctiin if ild peiple,it has satisfied clinical curative effect,it is safe and reliable,and it is wirth clinical applicatiin.