Hydrolysis Kinetics of 2-Pyridinecarboxamide, 3-Pyridinecarboxamide and 4-Pyridinecarboxamide in High-Temperature Water

高温液态水中2-吡啶甲酰胺、3-吡啶甲酰胺、4-吡啶甲酰胺的水解反应动力学(英文)

A kinetic study is reported here on hydrolysis of three pyridinecarboxamides in high-temperature water in the temperature range of 190-250℃ at 8 MPa. 2-Pyridinecarboxamide, 3-pyridinecarboxamide and 4-pyridinecarboxamide hydrolyze to corresponding picolinic acids. 2-Picolinic acid is further decarboxylated to pyridine. Experiments at different temperatures show that the first-order rate constants display an Arrhenius behavior with activation energies of （110.9 ±2.3）, （70.4 ± 2.1） and （61.4 ± 1.8）kJ.mo1-1 for 2- pyridinecarboxamide, 3-pyridinecarboxamide and 4-pyridinecarboxamide, respectively. These kinetic parameters for pyridinecarboxamide hydrolysis are more reliable and accurate than those from the consecutive hydrolysis of cyanopyridines.

A kinetic study is reported here on hydrolysis of three pyridinecarboxamides in high-temperature water in the temperature range of 190–250 °C at 8 MPa. 2-Pyridinecarboxamide, 3-pyridinecarboxamide and4-pyridinecarboxamide hydrolyze to corresponding picolinic acids. 2-Picolinic acid is further decarboxylated to pyridine. Experiments at different temperatures show that the first-order rate constants display an Arrhenius behavior with activation energies of(110.9 ± 2.3),(70.4 ± 2.1) and(61.4 ± 1.8) kJ·mol-1for 2-pyridinecarboxamide, 3-pyridinecarboxamide and 4-pyridinecarboxamide, respectively. These kinetic parameters for pyridinecarboxamide hydrolysis are more reliable and accurate than those from the consecutive hydrolysis of cyanopyridines.