期刊文献+

癫痫持续状态患者的临床治疗探析

Study on Clinical Treatment for Patients With Epilepticus Status
下载PDF
导出
摘要 目的探讨地西泮联合丙戊酸治疗癫痫持续状态的效果。方法选取我院在2013年2月∽2015年3月收治的72例癫痫持续状态患者,根据平均法将其分成两组,观察组36例,采用地西泮联合丙戊酸治疗,对照组36例,采用单纯的地西泮治疗,评估并对比两组患者的治疗情况。结果观察组36例患者中,治疗有效率为91.67%,对照组36例患者中,治疗有效率为75%,两组患者均未出现严重不良反应,观察组的治疗效果优于对照组,差异有统计学意义(P〈0.05)。结论应用地西泮联合丙戊酸治疗癫痫持续状态的效果显著,并能够减少患者不良反应的发生。 Objective Effect of diazepam combined with valproate in treatment of patients with epilepticus status is to be studied. Methods Chose 72 patients of epilepticus status who were treated in our hospital from February 2013 to March 2015 and separated them into two groups according to average method. 36 patients in study group were given diazepam combined with valproate and 36 patients in control group were given diazepam only,then assessed and compared patients' treatment effects between two groups. Results 36 patients' treatment efficacy in study group was 91.67%,while 36 patients' treatment efficacy in control group was 75%,and there was no severe adverse reactions,treatment efficacy in study group was much higher than that in control group,there was a treatment differential between two groups and such a differential has statistic value(P〈0.05). Conclusion Diazepam combined with valproate is of efficacy in treatment of patients with epilepticus status,it is conducive to reducing patients' adverse reactions.
作者 陈军
出处 《中国卫生标准管理》 2015年第16期28-30,共3页 China Health Standard Management
关键词 癫痫持续状态 地西泮 丙戊酸 临床效果 Epilepticus status Diazepam Valproate Clinical efficacy
  • 相关文献

参考文献4

二级参考文献36

  • 1陈春富,郎森阳,贾海燕,夏程,王湘庆.癫痫持续状态患者发生多器官功能障碍的危险因素分析[J].中华流行病学杂志,2006,27(7):618-622. 被引量:16
  • 2吴逊.我国癫痫的诊断与治疗现状[J].中国现代神经疾病杂志,2007,7(3):201-203. 被引量:10
  • 3Rossetti A O, Logroscino G, MiUigan T A, et al. Status Epilepticus Severity Score (STESS) : a tool to orient early treatment strategy[ J]. J Neurol, 2008, 255(10) : 1561 - 1566.
  • 4Garzon E, Fernandes R M, Sakamoto A C. Analysis of clinical charac- teristics mad risk factors for mortality in human status epileptieus [ J ]. Seizure, 2003, 12(6) : 337 -345.
  • 5Rossetti A O, Logroscino G, Bromfield E B. A clinical score for prog- nosis of status epileptieus in adults[ J ]. Neurology, 2006, 66 (11): 1736 - 1738.
  • 6Holtkamp M, Othman J, Buchheim K, et al. A "malignant" variant ofstatus epilepticus[J]. Areh Neurol, 2005, 62(9) : 1428 -1431.
  • 7Towne A R, Pellock J M, Ko D, et al. Determinants of mortality in status epilepticus[ J]. Epilepsia, 1994, 35 (1) : 27 - 34.
  • 8Sankar R, Shin D H, Liu H, et al. Patterns of status epilepticus-in- duced neuronal injury during development and long-term consequences [J]. J Neurosci, 1998, 18(20): S3S2 -S393.
  • 9Cole A J. Is epilepsy a progressive disease? The neurobiologieal conse- quences of epilepsy [ J ]. Epilepsia, 2000, 41 Suppl 2 : S13 - $22.
  • 10Bleck T P. Management approaches to prolonged seizures and status epilepticus[J]. Epilepsia, 1999, 40 Suppl 1 : $59 - $63.

共引文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部