康复训练结合柴胡疏肝汤辩证治疗对脑卒中后抑郁的作用

Effect of rehabilitation training combined with Chaihu shuga tang differentiating syndromes in treating the post stroke depression

目的探讨康复训练结合柴胡疏肝汤辩证治疗对脑卒中后抑郁(PSD)的疗效及患者神经功能缺损和日常生活活动(ADL)能力的影响。方法将80例PSD患者用随机分为对照组和治疗组,每组40例。所有的患者给予常规药物治疗,对照组采用康复训练,治疗组在对照组治疗的基础上加柴胡疏肝汤治疗。两组患者分别与治疗前24h及治疗4周后进行汉密顿抑郁量表(HAMD)、神经功能缺损程度量表(NDS)、和Barthel指数(BI)评定。结果治疗4周后,两组患者的HAMD、NDS及BI评分较治疗前明显改善(p<0.05),治疗组的HAMD、NDS及BI评分改善幅度均显著优于对照组,差异有统计学意义(p<0.05)。结论康复训练结合柴胡疏肝汤辩证治疗PSD患者,疗效显著,同时促进患者神经功能的康复,提高ADL能力。

To investigate the effect of rehabilitation training combined with Chaihu shugan tang differentiating syndromes in treating the post stroke depression（ PSD）,and to observe the impact on the activities of daily living（ ADL） and neural function impairment. Methods 80 PSD patients were randomly divided into the control group and the treatment group with 40 case in each.All the patients received routine therapy of drug,the control group used rehabilitation training while the treatment group added Chaihu shugan tang based on the treatment of the control group. To assess Hamilton Rating Scale for Depression（ HAMD） 、neurological deficit score（ NDS） and Barthel Index（ BI） of the patients in 2 groups respectively 24 h before treatment and 4 weeks after treatment. Results After 4 weeks of treatment,the the Scores of HAMD 、BI and NDS in 2 group patients were improved more than before treatment（ p〈 0. 05）,and the treatment group was difference statistically significant compared with the control group（ p〈 0. 05）. Conclusion There is significant effect on rehabilitation training combined with Chaihu shugan tang therapy to the PSD,promoting the rehabilitation of neural function and improving the ADL performance simultaneously.